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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Anemia is associated with poor outcomes in patients with less severe ischemic stroke
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Anemia is associated with poor outcomes in patients with less severe ischemic stroke

机译：缺血性中风较轻的患者贫血与预后不良相关

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Anemia is a known predictor of in-hospital mortality among patients with such vascular conditions as acute myocardial infarction, congestive heart failure, and chronic kidney disease. The role of anemia in patients with acute ischemic stroke is less well understood. We sought to examine the association between anemia at hospital admission and the combined outcome of in-hospital mortality and discharge to hospice in patients with acute ischemic stroke. We evaluated data from a retrospective cohort of consecutive ischemic stroke patients presenting within 48 hours of symptom onset at 5 hospitals between 1998 and 2003. Anemia was defined as an admission hematocrit value of <30%. Less severe stroke was defined as an admission National Institutes of Health Stroke Scale score of <10. The outcome was the combined endpoint of in-hospital mortality or discharge to hospice. Among 1306 patients with stroke, anemia was present on admission in 6.4%, and the combined outcome of death or discharge to hospice was present in 10.1%. Anemia was not associated with outcome in patients with severe stroke (anemia, 17.2% [5 of 29] vs no anemia, 28,4% [98 of 345]; P =.20), but was associated with outcome in patients with less severe stroke (anemia, 13.0% [7 of 54] vs no anemia, 2.5% [22 of 878]; P <.0001). After adjustment for stroke severity, admission anemia was independently associated with outcome in patients with less severe stroke (adjusted odds ratio, 4.17; 95% confidence interval, 1.47-11.90), but not in patients with more severe strokes (adjusted odds ratio, 0.82; 95% confidence interval, 0.30-2.22). Our data indicate that anemia is associated with in-hospital mortality or discharge to hospice in patients with less severe ischemic stroke.
机译：贫血是血管疾病如急性心肌梗塞，充血性心力衰竭和慢性肾脏病患者中院内死亡率的已知预测因子。贫血在急性缺血性中风患者中的作用还不太清楚。我们试图检查急性缺血性卒中患者入院时贫血与院内死亡率和临终院出院的综合结果之间的关系。我们评估了1998年至2003年间5所医院在症状发作后48小时内出现症状的连续缺血性卒中患者的回顾性队列研究数据。贫血定义为入院血细胞比容值<30％。轻度中风定义为入院美国国立卫生研究院中风量表评分<10。结果是院内死亡率或临终院出院的综合终点。在1306名中风患者中，入院时出现贫血的比例为6.4％，死于或临终临终的合并结果的比例为10.1％。贫血与重度卒中患者的预后无关（贫血，17.2％[5/29] vs无贫血，28.4％[98/345]; P = .20），但与轻度卒中患者的预后相关重度中风（贫血，占13.0％[54分中的7个]，而无贫血，占2.5％[878个中的22个]; P <.0001）。在对卒中严重程度进行调整之后，入院贫血与卒中程度较轻的患者（校正比值比为4.17; 95％置信区间为1.47-11.90）独立相关，但卒中较重的患者则不相关（校正比值比为0.82） ; 95％置信区间0.30-2.22）。我们的数据表明，缺血性中风较轻的患者贫血与院内死亡率或临终院出院有关。

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