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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Cardiac Troponin I after Carotid Endarterectomy in Different Cardiac Risk Patients
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Cardiac Troponin I after Carotid Endarterectomy in Different Cardiac Risk Patients

机译:不同心脏风险患者的颈动脉内膜切除术后心脏肌钙蛋白I

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Background: We compared postoperative cardiac damage, defined as cardiac troponin I (cTnI) elevation, in low, medium, and high cardiac risk patients, after carotid endarterectomy (CEA). Methods: The Vascular Study Group of New England Cardiac Risk Index (VSG-CRI) criteria for stratifying patients considered for vascular surgery into low, medium, and high cardiac risk groups were used prospectively. For all patients (n = 324), cTnI value assessments were made before surgery and on postoperative days 1, 3, and 7. Postoperative cTnI values ranging from .05 to .5 ng/mL were classified as myocardial ischemia; values more than .5 ng/mL were classified as myocardial infarction. Cardiac damage was defined as either myocardial ischemia or infarction. Results: Mortality was .003%, stroke rate was null, and symptomatic myocardial infarction was null as well. Low-risk patients (16 of 140) and medium-risk patients (28 of 160) increased their troponin levels on days 1 and 3 postoperatively. However, none of the high-risk patients (n 5 24) showed any postoperative cardiac damage. Low and medium cardiac risk patients showed higher troponin values on each separate day, in comparison with high cardiac risk patients. Conclusions: CEA is followed by a high incidence of asymptomatic cTnI increase that is associated with late cardiac events. However, high cardiac risk patients as defined by the VSG-CRI criteria do not seem to suffer higher cardiac damage after CEA compared with low and medium cardiac risk patients.
机译:背景:我们比较了在低,中和高心脏风险患者中,在颈动脉内膜切除术(CEA)后的心脏损伤程度,即心肌肌钙蛋白I(cTnI)升高。方法:前瞻性地使用了新英格兰心血管疾病风险指数研究组(VSG-CRI)的标准,该标准将考虑进行血管手术的患者分为低,中和高心脏风险组。对于所有患者(n = 324),均在术前以及术后第1、3和7天进行了cTnI值评估。术后cTnI值范围从0.05到0.5 ng / mL被归类为心肌缺血。大于.5 ng / mL的值被分类为心肌梗塞。心脏损害定义为心肌缺血或梗塞。结果:死亡率为0.003%,卒中率为零,有症状的心肌梗死也为零。低风险患者(140名患者中的16名)和中风险患者(160名患者中的28名)在术后第1天和第3天增加了肌钙蛋白水平。但是,没有高危患者(n = 5 24)显示任何术后心脏损害。与具有高心脏风险的患者相比,具有低心脏风险的患者在每一天都显示更高的肌钙蛋白值。结论:CEA继之以无症状性cTnI升高的高发生率,这与晚期心脏事件有关。然而,由VSG-CRI标准定义的高心脏风险患者似乎与低和中度心脏风险患者相比,CEA后并未遭受更高的心脏损害。

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