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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Efficiency of the Penumbra 5MAX ACE Reperfusion Catheter in Acute Ischemic Stroke Patients
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Efficiency of the Penumbra 5MAX ACE Reperfusion Catheter in Acute Ischemic Stroke Patients

机译：半影5MAX ACE再灌注导管对急性缺血性中风患者的疗效

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Objective: This study was performed to investigate whether the Penumbra 5MAX ACE is superior to other Penumbra systems. Materials and Methods: We performed a retrospective, single center analysis of patients with acute ischemic stroke with occlusion of the internal carotid artery or middle cerebral artery (M1 segment) who underwent endovascular therapy using a Penumbra system. The reperfusion success rate, puncture-to-revascularization time, and number of passes were assessed. Multivariate regression analysis was conducted to evaluate independent factors related to revascularization within 60 minutes. Successful revascularization was defined by a thrombolysis in cerebral infarction score >= 2b. Results: The Penumbra 5MAX ACE was used in 24 of the 40 patients (60%). Although the revascularization success rate was similar between patient groups (P = .229), the number of passes was significantly lower (1.5 +/- .8 versus 2.6 +/- 1.3, P = .006) and the puncture-to-revascularization time was shorter (50 +/- 26 minutes versus 116 +/- 69 minutes, P = .002) in patients treated with the Penumbra 5MAX ACE. The Penumbra 5MAX ACE was identified as an independent factor for early revascularization (odds ratio, 5.80; P = .041). Among patients with a premorbid modified Rankin Scale score of 0-1, a modified Rankin Scale score of 0-2 at 3 months was observed in 15 of the 19 patients (79%) treated with the Penumbra 5MAX ACE and in 8 of the 16 (50%) who were not (P = .072). Conclusion: Acute revascularization therapy using the Penumbra 5MAX ACE can achieve rapid successful recanalization and tend to improve clinical outcomes.
机译：目的：进行这项研究是为了研究Penumbra 5MAX ACE是否优于其他Penumbra系统。材料和方法：我们对急性缺血性卒中并阻塞了颈内动脉或大脑中动脉（M1段）的患者进行了回顾性单中心分析，这些患者接受了Penumbra系统进行了血管内治疗。评估了再灌注成功率，穿刺至血运重建时间和通过次数。进行了多元回归分析，以评估与60分钟内血运重建相关的独立因素。血栓溶解≥2b定义为成功的血运重建。结果：40例患者中有24例使用了Penumbra 5MAX ACE（60％）。尽管患者组之间的血运重建成功率相似（P = .229），但通过次数明显减少（1.5 +/- .8对2.6 +/- 1.3，P = .006）和穿刺至血运重建Penumbra 5MAX ACE治疗的患者的时间较短（50 +/- 26分钟，而116 +/- 69分钟，P = .002）。 Penumbra 5MAX ACE被确定为早期血运重建的独立因素（优势比为5.80; P = .041）。在病前修正后的Rankin量表评分为0-1的患者中，在接受Penumbra 5MAX ACE治疗的19例患者中有15例（79％）在3个月时观察到改良的Rankin量表评分为0-2。 （50％）谁不是（P = .072）。结论：使用Penumbra 5MAX ACE进行的急性血运重建治疗可以快速成功地实现再通，并可以改善临床疗效。

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