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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Diffusion-Weighted MRI in Evaluation of Transient Ischemic Attack
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Diffusion-Weighted MRI in Evaluation of Transient Ischemic Attack

机译：弥散加权磁共振成像评估短暂性脑缺血发作

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摘要

Diffusion-weighted magnetic resonance imaging (DWI) is a sensitive diagnostic tool for detecting recent ischemic lesions in patients with transient ischemic attacks (TIAs), but the interpretation of the presence or absence of DWI abnormalities in TIA patients still remains controversial, To elucidate the pathophysiology underlying those lesions, we analyzed DWI abnormalities in patients with recent TIAs. Based on 45 consecutive patients with TIAs who underwent DWI within 10 days of onset, demographic data and clinical manifestations were analyzed in relation to the DWI abnormalities. According to the method utilized in the Oxfordshire Community Stroke Study, clinical manifestations were classified into classical lacunar syndrome and non-lacunar symptoms. Based on the vascular distributions of ischemic lesions, the DWI abnormalities were classified into small-vessel and large-vessel lesions. DWI abnormalities were detected in 14 (31%) of 45 TIA patients. Seven (50%) of 14 DWI-positive patients had occlusive vascular lesions on intracranial magnetic resonance angiography, while only 5 (16%) of 31 DWI-negative patients had occlusive lesions (P < .05). No other demographic or clinical features, including risk factor and presence of cardiac disease, differed significantly between the DWI-positive and DWI-negative patient groups. Four (46%) of 9 DWI-positive patients who had a classical lacunar syndrome also showed small-vessel lesions on DWI, whereas all 5 patients who had non-lacunar symptoms showed large-vessel lesions. We concluded that although DWI abnormalities were detected in only one third of our TIA patients, DWI abnormalities were closely related to intracranial vascular occlusive lesions. The combination of DWI and MRA was useful for detecting large-artery lesions in patients displaying a classical lacunar syndrome.
机译：弥散加权磁共振成像（DWI）是用于检测短暂性脑缺血发作（TIA）患者近期缺血性病变的灵敏诊断工具，但对于TIA患者是否存在DWI异常的解释仍然存在争议，这些病变的病理生理学基础上，我们分析了近期TIA患者的DWI异常。根据发病的10天内接受DWI的45例连续的TIA患者，分析了与DWI异常相关的人口统计学数据和临床表现。根据牛津郡社区卒中研究中使用的方法，临床表现分为经典腔隙综合征和非腔隙性症状。根据缺血性病变的血管分布，将DWI异常分为小血管病变和大血管病变。 45例TIA患者中有14例（31％）检测到DWI异常。 14例DWI阳性患者中有7例（50％）在颅内磁共振血管造影上有闭塞性血管病变，而31例DWI阴性患者中只有5例（16％）有闭塞性病变（P <.05）。 DWI阳性和DWI阴性的患者组之间没有其他人口统计学或临床特征，包括危险因素和心脏病的存在。 9例患有经典腔隙综合征的DWI阳性患者中，有4例（46％）在DWI上也显示了小血管病变，而所有5例非腔隙性症状的患者均显示了大血管病变。我们得出的结论是，尽管仅在我们的TIA患者中检测到DWI异常，但DWI异常与颅内血管闭塞性病变密切相关。 DWI和MRA的组合可用于检测表现出典型腔隙综合征的患者的大动脉病变。

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