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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Isolated Broca's Area Aphasia and Ischemic Stroke Mechanism
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Isolated Broca's Area Aphasia and Ischemic Stroke Mechanism

机译：孤立性布罗卡氏区失语症与缺血性中风机制

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摘要

Cerebral embolism has been considered to be the most common stroke mechanism when the resulting stroke has at least some amount of aphasia as part of its clinical manifestations. To determine stroke mechanism and risk factor profile in patients with isolated Broca's area aphasia (Broca's infarct), we studied 34 consecutive patients with recent infarcts whose only or predominant clinical feature was that of nonfluent speech and compared these cases with 68 control patients with cortical infarcts in the middle cerebral artery distribution whose clinical features were not restricted to an isolated aphasia. Controls were age- and sex-matched and were selected from ischemic infarcts seen at our institutions over the same observation period. Broca's infarct patients had significantly more cardiac-source emboli, more cardiac thrombi identified on echocardiography, and less large-artery atherosclerosis (each P = .02). These differences in stroke mechanism may suggest different diagnostic and therapeutic decision making for those ischemic stroke patients presenting with isolated Broca's aphasia.
机译：当导致的中风至少有一定程度的失语症作为其临床表现的一部分时，脑栓塞被认为是最常见的中风机制。为了确定孤立的布罗卡氏区失语症（布罗卡氏梗死）患者的中风机制和危险因素谱，我们研究了34例最近发生梗死的连续患者，其唯一或主要临床特征是语言不流利，并将这些病例与68例患有皮质梗死的对照患者进行了比较在大脑中动脉分布中，其临床特征不限于孤立的失语症。对照是年龄和性别匹配的，并且选自在同一观察期内在我们机构中发现的缺血性梗死。 Broca梗死患者的心脏源栓塞明显多，超声心动图检查发现的心脏血栓更多，大动脉粥样硬化的发生率更低（每个P = .02）。中风机制的这些差异可能提示那些患有孤立的Broca失语症的缺血性中风患者做出不同的诊断和治疗决策。

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