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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Knowledge Regarding Oral Anticoagulation Therapy among Patients with Stroke and Those at High Risk of Thromboembolic Events
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Knowledge Regarding Oral Anticoagulation Therapy among Patients with Stroke and Those at High Risk of Thromboembolic Events

机译：中风和血栓栓塞事件高风险患者的口服抗凝治疗知识

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Background: Apart from atrial fibrillation, indications for oral anticoagulation common in our clinical practice include rheumatic heart disease and mechanical heart valve replacement. Evaluation of current patient knowledge regarding oral anticoagulation therapy (OAT) is the first step in improving the quality of anticoagulation therapy and patient care. The aim of the present study was to assess the knowledge regarding OAT among patients with stroke and those at high risk of thromboembolic events in a tertiary care hospital in India. Methods: A descriptive cross-sectional design was used; 240 patients on OAT because of various indications (mechanical heart valve replacement, rheumatic heart disease, atrial fibrillation, and stroke) attending the neurology and cardiology outpatient clinics and inpatient services were recruited. A structured self-developed questionnaire was used to assess the knowledge in these patients. Results: Most patients (62.9%) were ignorant about the target prothrombin time/international normalized ratio (PT/INR) levels with only 30% having their recent INR within the target range; 50% of the patients had a poor knowledge score, and the knowledge gap was most prominent in the domains of dietary interactions followed by drug interactions, adverse effects, and PT/INR monitoring. Knowledge score also had a significant association with gender, education, monthly income, and place of residence (P < .05). Conclusion: Patient's knowledge about OAT was suboptimal. The findings support the need for educational interventions to improve the knowledge regarding OAT and, thereby, achieve an appropriate and safe secondary prevention of stroke.
机译：背景：除房颤外，我们临床实践中常见的口服抗凝适应症包括风湿性心脏病和机械性心脏瓣膜置换术。评估当前有关口服抗凝治疗（OAT）的患者知识是提高抗凝治疗和患者护理质量的第一步。本研究的目的是评估印度三级医院中风和血栓栓塞事件高风险患者的OAT知识。方法：采用描述性横截面设计;招募了240名因各种适应症（机械性心脏瓣膜置换，风湿性心脏病，心房颤动和中风）而需要接受OAT治疗的患者，就诊于神经内科和心脏病科门诊和住院服务。结构化的自行开发的调查表用于评估这些患者的知识。结果：大多数患者（62.9％）对目标凝血酶原时间/国际标准化比率（PT / INR）水平一无所知，只有30％的患者最近的INR在目标范围内。 50％的患者知识得分差，并且知识差距在饮食相互作用领域中最为突出，其次是药物相互作用，不良反应和PT / INR监测。知识得分也与性别，教育程度，月收入和居住地密切相关（P <.05）。结论：患者对OAT的了解不佳。这些发现支持需要采取教育干预措施来提高有关OAT的知识，从而实现中风的适当和安全的二级预防。

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