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Is Stroke the Most Common Cause of Disability?

机译:中风是导致残疾的最常见原因吗?

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Background: It is widely stated that stroke is the most common cause of severe disability. We aimed to examine whether this claim is supported by any evidence. Methods: We conducted secondary analysis of the Office of National Statistics 1996 Survey of Disability, United Kingdom. This was a multistage stratified random sample of 8683 noninstitutionalized individuals aged between 16 and 101 years, mean 62 years, response rate 83% (n = 8816). The outcome used was the Office of Population Censuses and Surveys severity scale for disability. Odds ratios and population-attributable fractions were calculated to examine the associations between diagnoses and disability. Results: Logistic regression modelling suggests that, after adjustment for comorbidity and age, those with stroke had the highest odds of reporting severe overall disability (odds ratio 4,88, 95% confidence interval [CI] .337-6.10). Stroke was also associated with more individual domains of disability than any of the other conditions considered. Adjusted population-attributable fractions were also calculated and indicated that musculoskeletal disorders had the highest population-attributable fraction (30.3%, 95% CI 26.2-34.1) followed by mental disorders (8.2%, 95% CI 6.9-9.5) and stroke (4.5%, 95% CI 3.6-5.3). Conclusion: Stroke is not the most common cause of disability among the noninstitutionalized United Kingdom population. However, stroke is associated with the highest odds of reporting severe disability. Importantly, stroke is associated with more individual domains of disability compared with other conditions and might be considered to be the most common cause of complex disability.
机译:背景:人们普遍认为中风是导致严重残疾的最常见原因。我们旨在检查该说法是否有任何证据支持。方法:我们对英国国家统计局1996年残疾调查进行了二次分析。这是一个多阶段分层随机抽样,对8683位年龄在16至101岁,平均62岁,未应答率83%(n = 8816)的非住院患者进行了随机抽样。所使用的结果是人口普查和调查办公室对残疾人的严重程度量表。计算赔率和人口归因分数,以检查诊断与残疾之间的关联。结果:Logistic回归模型表明,对合并症和年龄进行调整后,中风患者报告严重整体残疾的几率最高(几率4,88,95%置信区间[CI] .337-6.10)。与其他任何考虑的疾病相比,中风还与更多的残疾领域相关。还计算了校正后的人群归因分数,结果表明,肌肉骨骼疾病的人群归因分数最高(30.3%,95%CI 26.2-34.1),其次是精神障碍(8.2%,95%CI 6.9-9.5)和中风(4.5) %,95%CI 3.6-5.3)。结论:在非制度化的英国人群中,中风不是致残的最常见原因。但是,中风与报告严重残疾的几率最高。重要的是,与其他情况相比,中风与更多的残疾领域有关,并且可能被认为是造成复杂残疾的最常见原因。

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