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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Prognosis of Early-Stage Continuous Electrocardiogram Abnormalities on Patients with Acute Ischemic Stroke
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Prognosis of Early-Stage Continuous Electrocardiogram Abnormalities on Patients with Acute Ischemic Stroke

机译：急性缺血性中风患者早期持续心电图异常的预后

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Background: To explore the effects of onset time of electrocardiogram (ECG) abnormalities at an early stage of acute ischemic stroke on patient prognosis. Cardiac dysfunction after stroke is a challenge for clinicians. This is a retrospective study of patients in the neurology departments of 23 hospitals in Shanghai and Wuhan, China. Methods: The medical records of 351 patients were compared. Chi-square, Kruskal-Wallis, Mann-Whitney U tests, and stratification compared subgroups. Logistic regressions analyzed factors associated with modified Rankin Scale (mRS) score. Results: ECG abnormalities occurred in 70.1% of patients at an early stage (most were within 48 hours of disease onset) at least once, whereas 45.9% of the patients had ECG abnormalities within 48 hours of onset and at 7 days after onset. The incidence of poor prognosis (mRS > 1) was significantly higher in the patients with ECG abnormalities for both time points than that in those with normal ECGs (56.3% versus 32%, odds ratio 5 2.166). Most patients demonstrated 1 to 2 ECG abnormalities, and very few patients had 3 or more. Increasing number of ECG abnormalities was mirrored by poorer prognosis. ECG abnormalities occurred within 48 hours and at the seventh day after onset of acute ischemic stroke; the abnormalities that appeared within 48 hours and were still found on the seventh day after onset of the disease were independent predictors of poor patient prognosis. Conclusions: The incidence of abnormal ECGs was high in the patients with acute ischemic stroke, and the abnormal ECGs could appear at any stage of the disease.
机译：背景：探讨急性缺血性卒中早期的心电图（ECG）异常发作时间对患者预后的影响。中风后心脏功能障碍是临床医生面临的挑战。这是对中国上海和武汉的23家医院神经内科患者的回顾性研究。方法：比较351例患者的病历。卡方检验，Kruskal-Wallis检验，Mann-Whitney U检验和分层比较了亚组。 Logistic回归分析了与改良的Rankin量表（mRS）得分相关的因素。结果：心电图异常在早期（至少在疾病发作的48小时内）发生一次，占70.1％的患者至少一次，而45.9％的患者在发病48小时内和发病后7天出现ECG异常。在两个时间点，心电图异常患者的不良预后发生率（mRS> 1）均显着高于正常心电图患者（56.3％对32％，比值比5 2.166）。大多数患者表现出1到2个ECG异常，很少有3个或更多的患者。预后较差反映了心电图异常数目的增加。心电图异常发生在急性缺血性卒中发作后的48小时内和第七天;在疾病发作后第48天出现并在第7天仍发现的异常是患者预后不良的独立预测因素。结论：急性缺血性脑卒中患者异常心电图的发生率较高，异常心电图可能出现在疾病的任何阶段。

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