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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Acquired Hemophilia A Associated with Internal Border-zone Infarction Triggered by Major Hemorrhage of Thigh and Leg: A Case Report
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Acquired Hemophilia A Associated with Internal Border-zone Infarction Triggered by Major Hemorrhage of Thigh and Leg: A Case Report

机译：大腿和腿部大出血引发的与内部边界区梗死相关的获得性血友病A例

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摘要

It is unusual to be complicated with cerebral infarction for bleeding disorders. We describe a first case of internal border-zone infarction (I-BZI) complicated with acquired hemophilia A. A 79-year-old man was introduced from other hospital by cerebral infarction and severe anemia. His left thigh and leg were swollen with subcutaneous bleeding. Activated partial thromboplastin time was 99.4 seconds. Factor VIII activity was less than 1% and Factor VIII inhibitor concentration was 85 BU, respectively. The platelet count and prothrombin time were normal. These results were consistent with the diagnosis of acquired hemophilia A. Magnetic resonance imaging of the brain showed multiple small infarction in bilateral internal border zone. To our knowledge, this is the first case of I-BZI complicated with acquired hemophilia A. This case suggested that major hemorrhage is one of the sole causes of I-BZI. (C) 2015 by National Stroke Association
机译：并发出血性脑梗塞是罕见的。我们描述了第一例内部边界区梗死（I-BZI）并发获得性血友病A。一名来自另一家医院的79岁男子因脑梗塞和严重贫血而入院。他的左大腿和小腿因皮下出血而肿胀。活化的部分凝血活酶时间为99.4秒。因子活性分别小于1％，1因子抑制剂浓度分别为85 BU。血小板计数和凝血酶原时间正常。这些结果与获得性血友病A的诊断是一致的。大脑的磁共振成像显示双侧内边界区有多个小梗塞。据我们所知，这是I-BZI并发获得性血友病A的第一例。该病例表明，大出血是I-BZI的唯一原因之一。 （C）国家卒中协会2015年

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