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首页> 外文期刊>Journal of the advanced practitioner in oncology >Human Herpesvirus-6 Encephalitis After Hematopoietic Stem Cell Transplantation
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Human Herpesvirus-6 Encephalitis After Hematopoietic Stem Cell Transplantation

机译：造血干细胞移植后的人类疱疹病毒6型脑炎

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Mrs. L was in good health until she was diagnosed with acute myeloid leukemia (AML) at the age of 63. She had presented to her primary care provider with a productive cough and was found to have pancytopenia, with 16% myeloid blasts on a peripheral blood draw. She was admitted to a major metropolitan hospital for treatment of suspected AML. A bone marrow biopsy was performed, resulting in 44% myeloid blasts with complex cytogenetic studies [46,XX,der(16)t(1;16)(q21;q24)[2]/46Iidem)t(4;16) (p12;q24)] and background ringed sideroblasts and dyserythropoiesis, implying underlying myelodysplasia in addition to AML. Molecular testing for FLT3, NPM1, and CE3PA was not performed, given the picture of antecedent myelodysplastic syndrome (MDS). The French-American-British classification system traditionally used for AML cases is no longer applicable for MDS in light of the system revisions in 2008.
机译：L夫人一直健康，直到她在63岁被诊断出患有急性髓细胞性白血病（AML）为止。她曾向初级保健提供者出现咳嗽，并发现患有全血细胞减少症，其中16％的髓样母细胞被感染。外周血抽。她被送往一家大都市医院接受治疗，以治疗疑似AML。进行了骨髓活检，结果产生了44％的髓母细胞，并进行了复杂的细胞遗传学研究[46，XX，der（16）t（1; 16）（q21; q24）[2] / 46Iidem）t（4; 16）（ p12; q24）]和背景呈环状的成铁细胞和促红细胞生成异常，这意味着除AML外还存在潜在的骨髓增生异常。鉴于先前的骨髓增生异常综合症（MDS）的图片，未对FLT3，NPM1和CE3PA进行分子测试。考虑到2008年的系统修订，传统上用于AML案件的法裔美英分类系统不再适用于MDS。

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