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首页> 外文期刊>Journal of the American Pharmacists Association: JAPhA >Drug therapy concerns questionnaire: initial development and refinement.
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Drug therapy concerns questionnaire: initial development and refinement.

机译：药物治疗涉及问卷：初步发展和完善。

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OBJECTIVE: To develop a scale, designed for self-administration, to assess patient perceptions of drug therapy problems (DTPs). DESIGN: Cross-sectional survey. SETTING: California Central Valley. PARTICIPANTS: 200 community-dwelling adults taking at least one prescription medication. MAIN OUTCOME MEASURE: 78 items assessing patient perceptions of DTPs. INTERVENTIONS: Self-administered questionnaire completed by study participants. RESULTS: Based on a Medication Evaluation and Response Model proposed in this article, items were developed to assess patient perceptions about potential or actual DTPs. Scales for five of the seven problem domains specified a priori were reliable based on participant responses: Perceived Efficacy, Overmedication Concerns, Adverse Drug Reaction Concerns, Adherence Issues, and Knowledge. Barriers and Intrusiveness were eliminated from, the questionnaire because of weak factor loadings. After making changes in domain assignment and eliminating redundant and weak items, five items remained in each of the five reliable scales, with Cronbach's alpha values ranging from 0.76 to 0.82. Each of the five scales was significantly associated with patient satisfaction with their medications. Individuals who reported fewer DTPs expressed greater overall satisfaction with their medications. In a forward stepwise regression analysis, four of the five scales exhibited independent associations with medication satisfaction, explaining 58.0% of the total variance in satisfaction [F(4,178) = 61.48, P < .0001]. Only the Knowledge scale failed to exhibit an independent association with satisfaction. CONCLUSION: The findings from this initial stage of scale development are encouraging. The association between the scales and medication satisfaction suggests that the scales may be useful in learning more about those factors that influence how patients evaluate their medications.
机译：目的：开发一种用于自我管理的量表，以评估患者对药物治疗问题（DTP）的看法。设计：横断面调查。地点：加利福尼亚中央谷地。参与者：200名居住在社区中的成年人，他们至少服用一种处方药。主要观察指标：78项评估患者对DTP的看法。干预措施：由研究参与者自行填写的问卷。结果：基于本文提出的药物评估和反应模型，开发了一些项目来评估患者对潜在或实际DTP的看法。根据参与者的回答，先验确定的七个问题域中的五个的量表是可靠的：感知效能，过度用药问题，药物不良反应问题，依从性问题和知识。由于弱因素负荷，从问卷中消除了障碍和干扰。在更改了域分配并消除了冗余项和弱项之后，五个可靠量表中的每个仍然保留了五个项，Cronbach的alpha值范围从0.76到0.82。五个量表中的每一个都与患者对药物的满意度显着相关。报告较少DTP的患者对药物的总体满意度较高。在前向逐步回归分析中，五个量表中的四个显示出与药物满意度的独立关联，解释了满意度总方差的58.0％[F（4,178）= 61.48，P <.0001]。只有知识量表未能表现出满意的独立关联。结论：从规模发展初期的结果令人鼓舞。量表与药物满意度之间的关联表明，这些量表可能有助于更多地了解那些影响患者评估其药物的因素。

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