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首页> 外文期刊>Journal of the American College of Radiology: JACR >Exposure to ionizing radiation and estimate of secondary cancers in the era of high-speed CT scanning: Projections from the medicare population
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Exposure to ionizing radiation and estimate of secondary cancers in the era of high-speed CT scanning: Projections from the medicare population

机译:高速CT扫描时代的电离辐射暴露和对继发性癌症的估计:医疗保险人群的预测

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Purpose: The aims of this study were to analyze the distribution and amount of ionizing radiation delivered by CT scans in the modern era of high-speed CT and to estimate cancer risk in the elderly, the patient group most frequently imaged using CT scanning. Methods: A retrospective cohort study was conducted using Medicare claims spanning 8 years (1998-2005) to assess CT use. The data were analyzed in two 4-year cohorts, 1998 to 2001 (n = 5,267,230) and 2002 to 2005 (n = 5,555,345). The number and types of CT scans each patient received over the 4-year periods were analyzed to determine the percentage of patients exposed to threshold radiation of 50 to 100 mSv (defined as low) and >100 mSv (defined as high). The National Research Council's Biological Effects of Ionizing Radiation VII models were used to estimate the number of radiation-induced cancers. Results: CT scans of the head were the most common examinations in both Medicare cohorts, but abdominal imaging delivered the greatest proportion (43% in the first cohort and 40% in the second cohort) of radiation. In the 1998 to 2001 cohort, 42% of Medicare patients underwent CT scans, with 2.2% and 0.5% receiving radiation doses in the low and high ranges, respectively. In the 2002 to 2005 cohort, 50% of Medicare patients received CT scans, with 4.2% and 1.2% receiving doses in the low and high ranges. In the two populations, 1,659 (0.03%) and 2,185 (0.04%) cancers related to ionizing radiation were estimated, respectively. Conclusions: Although radiation doses have been increasing along with the increasing reliance on CT scans for diagnosis and therapy, using conservative estimates with worst-case scenario methodology, the authors found that the risk for secondary cancers is low in older adults, the group subjected to the most frequent CT scanning. Trends showing increasing use, however, underscore the importance of monitoring CT utilization and its consequences.
机译:目的:本研究的目的是分析在现代高速CT时代通过CT扫描传送的电离辐射的分布和数量,并估计老年人(最常使用CT扫描成像的患者组)的癌症风险。方法:一项回顾性队列研究使用了长达8年(1998-2005年)的Medicare索赔进行评估,以评估CT的使用。在1998年至2001年(n = 5,267,230)和2002年至2005年(n = 5,555,345)的两个4年队列中分析了数据。分析每位患者在4年期间接受的CT扫描的次数和类型,以确定暴露于50至100 mSv(定义为低)和> 100 mSv(定义为高)的阈值辐射的患者百分比。国家研究委员会的“电离辐射VII的生物效应”模型用于估算辐射诱发的癌症数量。结果:在两个Medicare队列中,头部CT扫描是最常见的检查,但是腹部成像所占的比例最大(第一组为43%,第二组为40%)。在1998年至2001年的队列中,有42%的Medicare患者接受了CT扫描,分别有2.2%和0.5%的患者接受了低剂量和高剂量的放射剂量。在2002年至2005年的队列中,有50%的Medicare患者接受了CT扫描,其中4.2%和1.2%接受了低剂量和高剂量。在这两个人群中,分别估计出与电离辐射有关的癌症为1,659(0.03%)和2,185(0.04%)。结论:尽管放射剂量随着对CT扫描的诊断和治疗越来越依赖而增加,但使用最坏情况下的保守估计方法,作者发现,老年人群继发癌症的风险较低。最频繁的CT扫描。但是,显示使用增加的趋势强调了监视CT利用率及其后果的重要性。

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