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首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >Scalp-recorded auditory P300 event-related potentials in new-onset untreated temporal lobe epilepsy.
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Scalp-recorded auditory P300 event-related potentials in new-onset untreated temporal lobe epilepsy.

机译：头皮记录的新发未经治疗的颞叶癫痫的听觉P300事件相关电位。

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摘要

We studied scalp-recorded auditory event-related potentials (ERPs) of 30 untreated patients with new-onset temporal lobe epilepsy and 30 age- and sex-matched normal controls. This study was designed to eliminate the effects of intractability of seizures and chronic use of antiepileptic drugs on P300 auditory ERPs. There were no statistically significant differences in both latency and amplitude of P300 between the two groups. Similar methods were also used to analyze component latencies and amplitudes of ERPs of 9 patients who had hippocampal sclerosis with comparison to control subjects. There were no statistically significant differences between these two groups as well. Our study evidently does not support temporal lobe sources of P300 scalp-recorded auditory ERPs. We also conclude that the scalp-recorded auditory ERPs procedure is not a useful tool to evaluate temporal lobe epilepsy.
机译：我们研究了30例未经治疗的新发颞叶癫痫患者和30例年龄和性别匹配的正常对照的头皮记录的听觉事件相关电位（ERP）。本研究旨在消除癫痫发作的顽固性和长期使用抗癫痫药对P300听觉ERP的影响。两组之间的P300潜伏期和幅度在统计学上均无统计学差异。与对照组相比，还使用了类似的方法来分析9名海马硬化患者的组件潜伏期和ERPs幅度。两组之间也没有统计学上的显着差异。我们的研究显然不支持P300头皮记录的听觉ERP的颞叶来源。我们还得出结论，头皮记录的听觉ERPs程序不是评估颞叶癫痫的有用工具。

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