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Structural MRI changes of the brain in depression.

机译:抑郁症时大脑的结构性MRI变化。

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摘要

For many years, investigators have been trying to identify the neuroanatomical structures responsible for the development of neuropsychiatric disorders, specifically depression and schizophreniform disorders. The available data were based on observations made in neurological patients who developed a psychiatric comorbid disorder following the neurologic insult. With the advances in high-resolution magnetic resonance imaging and functional neuroimaging studies, we have witnessed in the last decade a wealth of new data that identify structural neuroimaging changes in mesial temporal structures, prefrontal cortex and basal ganglia in major depressive disorders. The purpose of this article is to briefly review the published data on neuroanatomical structural changes associated with major depressive and bipolar disorders.
机译:多年以来,研究人员一直在尝试寻找导致神经精神疾病(尤其是抑郁症和精神分裂症)发展的神经解剖结构。现有的数据基于对神经病患者发生神经精神共病的神经病患者的观察结果。随着高分辨率磁共振成像和功能性神经影像学研究的发展,在过去的十年中,我们目睹了许多新数据,这些数据可确定主要抑郁症患者中颞叶结构,前额叶皮层和基底神经节的结构性神经影像学变化。本文的目的是简要回顾与主要抑郁症和双相情感障碍相关的神经解剖结构变化的已发表数据。

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