首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >Use of normative databases and statistical methods in demonstrating clinical utility of QEEG: importance and cautions.
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Use of normative databases and statistical methods in demonstrating clinical utility of QEEG: importance and cautions.

机译:规范性数据库和统计方法在证明QEEG临床应用中的应用:重要性和注意事项。

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摘要

The clinical utility of the EEG, especially in psychiatric, learning and cognitive disorders, has been greatly enhanced by the use of quantitative analysis (QEEG) and comparisons to a normative database. Of primary importance in the use of such a reference database are the following considerations and cautions: adequate sampling across a broad age range; consideration of inclusion/exclusion criteria; adequate sample of artifact-free data to demonstrate reliability and replicability of norms; demonstration of specificity and sensitivity. A normative database meeting these criteria allows the multivariate description of patterns of QEEG abnormalities in patients as compared to age appropriate normative values, and the exploration of neurophysiological heterogeneity within populations. Demonstrations of the clinical significance of this approach exist in the scientific literature and demonstrate that QEEG provides high sensitivity and specificity to abnormalities in brain function seen in psychiatric populations.
机译:通过使用定量分析(QEEG)和与规范数据库的比较,大大提高了EEG的临床效用,特别是在精神病,学习和认知障碍方面。在使用这种参考数据库时,最重要的是以下注意事项和注意事项:在广泛的年龄范围内进行足够的抽样;考虑纳入/排除标准;足够的无伪造数据样本,以证明规范的可靠性和可复制性;展示特异性和敏感性。符合这些标准的规范数据库允许与年龄适当的规范值相比对患者的QEEG异常模式进行多变量描述,并探索人群中神经生理学的异质性。在科学文献中已经证明了这种方法的临床意义,并证明QEEG对精神病患者的脑功能异常具有高度的敏感性和特异性。

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