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首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >EEG does not predict response of manic patients to atypical antipsychotics.
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EEG does not predict response of manic patients to atypical antipsychotics.

机译：脑电图不能预测躁狂患者对非典型抗精神病药的反应。

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摘要

Previous investigations of the role of EEG in predicting response of bipolar or schizoaffective patients to psychotropic medications have yielded mixed results. In studies of valproate treated patients by McElroy and colleagues responders were more likely to have EEGs with nonparoxysmal abnormalities. However, in the placebo controlled trial done by the same group, responders and nonresponders did not differ with respect to such EEG abnormalities. Reeves and colleagues showed that patients presenting with mania and EEG abnormalities, particularly sharp activity, were statistically more likely to respond to the anticonvulsant mood stabilizer valproate than to lithium. The purpose of this investigation was to further assess the role of EEG in predicting the likelihood of response of patients with mania to certain other anticonvulsants (carbamazepine and lamotrig-ine) and atypical antipsychotic agents (olanzapine, risperidone, quetiapine, and ziprasidone).
机译：先前有关脑电图在预测双相情感障碍或精神分裂症患者对精神药物反应中的作用的调查得出了不同的结果。 McElroy及其同事在对丙戊酸治疗的患者进行的研究中，应答者更有可能患有非阵发性异常的脑电图。但是，在同一小组进行的安慰剂对照试验中，对于此类EEG异常，反应者和非反应者并无差异。 Reeves及其同事表明，患有躁狂和脑电图异常（特别是剧烈活动）的患者在统计学上对丙戊酸抗惊厥情绪稳定剂的反应比对锂更可能。这项研究的目的是进一步评估脑电图在预测躁狂症患者对某些其他抗惊厥药（卡马西平和拉莫三嗪）和非典型抗精神病药（奥氮平，利培酮，喹硫平和齐拉西酮）反应的可能性中的作用。

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