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首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >nCPAP treatment of obstructive sleep apnea increases slow wave sleep in prefrontal EEG.
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nCPAP treatment of obstructive sleep apnea increases slow wave sleep in prefrontal EEG.

机译：nCPAP治疗阻塞性睡眠呼吸暂停可增加前额叶脑电图的慢波睡眠。

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摘要

According to standard sleep stage scoring, sleep EEG is studied from the central area of parietal lobes. However, slow wave sleep (SWS) has been found to be more powerful in frontal areas in healthy subjects. Obstructive sleep apnea syndrome (OSAS) patients often suffer from functional disturbances in prefrontal lobes. We studied the effects of nasal Continuous Positive Airway Pressure (nCPAP) treatment on sleep EEG, and especially on SWS, in left prefrontal and central locations in 12 mild to moderate OSAS patients. Sleep EEG was recorded by polysomnography before treatment and after a 3 month nCPAP treatment period. Recordings were classified into sleep stages. No difference was found in SWS by central sleep stage scoring after the nCPAP treatment period, but in the prefrontal lobe all night S3 sleep stage increased during treatment. Furthermore, prefrontal SWS increased in the second and decreased in the fourth NREM period. There was more SWS in prefrontal areas both before and after nCPAP treatment, and SWS increased significantly more in prefrontal than central areas during treatment. Regarding only central sleep stage scoring, nCPAP treatment did not increase SWS significantly. Frontopolar recording of sleep EEG is useful in addition to central recordings in order to better evaluate the results of nCPAP treatment.
机译：根据标准的睡眠阶段评分，从顶叶的中央区域研究睡眠脑电图。然而，在健康受试者的额叶区域，慢波睡眠（SWS）的功能更为强大。阻塞性睡眠呼吸暂停综合症（OSAS）患者通常患有额叶前叶功能障碍。我们研究了12例轻度至中度OSAS患者的鼻前持续气道正压通气（nCPAP）治疗对睡眠脑电图，特别是对SWS的影响。在治疗前和nCPAP治疗3个月后通过多导睡眠图记录睡眠脑电图。记录分为睡眠阶段。在nCPAP治疗期之后，通过中央睡眠阶段评分在SWS中没有发现差异，但是在前额叶中，整个夜间S3睡眠阶段在治疗期间增加了。此外，前额叶SWS在第二NREM期增加，在第四NREM期减少。在nCPAP治疗前后，前额叶区域的SWS都更多，并且在治疗过程中前额叶的SWS显着高于中部区域。仅就中央睡眠阶段评分而言，nCPAP治疗并未显着增加SWS。除中央记录外，睡眠脑电图的前极记录也是有用的，以便更好地评估nCPAP治疗的结果。

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