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首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >The prognostic significance of interictal epileptiform activity in postoperative EEGs of patients with mesial temporal lobe epilepsy.
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The prognostic significance of interictal epileptiform activity in postoperative EEGs of patients with mesial temporal lobe epilepsy.

机译：颞中叶癫痫患者发作后脑电图发作间期癫痫样活动的预后意义。

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摘要

It has not been established whether electroencephalography (EEG) is a contributing factor in predicting the outcome of surgery for epilepsy. We conducted a prospective study on 26 patients (M/F 14/12, age: 33 +/- 7.5 years, range 19-48) with mesial temporal lobe epilepsy (MTLE) who were followed for 2 years after surgery and who underwent routine EEG recordings 5.6 +/- 3 months (range 3-12) postoperatively. Interictal epileptiform activity (IEA) on the EEG was compared in 17 seizure-free patients to 9 patients with recurrent seizures. The two groups were similar in gender, age, febrile convulsions, trauma, family history, seizure frequency prior to surgery, epilepsy duration and number of antiepileptic drugs. Following surgery, 17 study patients (65%) became seizure free; 9 (35%) had seizure recurrence. Post-operative EEG recordings showed IEA in 8/26 study patients (31%), 3 of whom were from the seizure-free group (3/17, 18%); 5 had seizure recurrence (5/9, 56%) (p=0.078). IEAs in postoperative EEGs were less frequently demonstrated in patients who were seizure free, but the presence of postoperative IEAs does not preclude successful surgical outcome.
机译：尚未确定脑电图（EEG）是否是预测癫痫手术结局的因素。我们对26例中度颞叶癫痫（MTLE）患者进行了前瞻性研究（男/女14/12，年龄：33 +/- 7.5岁，范围19-48），他们在术后2年进行了随访并接受了常规检查术后EEG记录为5.6 +/- 3个月（范围3-12）。比较了17例无癫痫发作患者和9例复发性癫痫发作患者的发作间期癫痫样活动（IEA）。两组在性别，年龄，高热惊厥，外伤，家族史，手术前癫痫发作频率，癫痫持续时间和抗癫痫药物数量方面相似。手术后，有17名研究患者（65％）无癫痫发作。 9例（35％）癫痫发作复发。术后脑电图记录显示8/26名研究患者的IEA（31％），其中3名来自无癫痫组（3/17，18％）; 5例发生癫痫复发（5/9，56％）（p = 0.078）。无癫痫发作的患者较少出现术后脑电图中的IEA，但术后IEA的存在并不排除手术成功的可能性。

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