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首页> 外文期刊>Journal of the American Academy of Dermatology >Guidelines for phototherapy of mycosis fungoides and Sezary syndrome: A consensus statement of the United States Cutaneous Lymphoma Consortium
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Guidelines for phototherapy of mycosis fungoides and Sezary syndrome: A consensus statement of the United States Cutaneous Lymphoma Consortium

机译:蕈样真菌病和Sezary综合征光疗指南:美国皮肤淋巴瘤协会的共识声明

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摘要

Background: Ultraviolet light (UVL) is a long established treatment for mycosis fungoides (MF) and Sezary syndrome (SS), subtypes of cutaneous T-cell lymphoma (CTCL). Treatments have traditionally included broadband, narrowband ultraviolet B light (UVB) and psoralen plus ultraviolet A light photochemotherapy (PUVA), but more recently, treatment options have expanded to include UVA1 and excimer laser. UVL is used either as monotherapy or as an adjuvant to systemic therapy, demonstrating efficacy in many cases that equal or surpass systemic medications. Despite its utility and duration of use, the current practice of using UVL guidelines for psoriasis to treat patients with MF/SS is problematic because the goals of prolonging survival and preventing disease progression are unique to CTCL compared to psoriasis.
机译:背景:紫外线(UVL)是一种治疗真菌病(MF)和Sezary综合征(SS)(皮肤T细胞淋巴瘤(CTCL)的亚型)的长期治疗方法。传统上,治疗方法包括宽带,窄带紫外线B光(UVB)和补骨脂素加紫外线A光化学疗法(PUVA),但最近,治疗选择已扩展到包括UVA1和准分子激光。 UVL可用作单一疗法或作为全身疗法的辅助剂,在许多等于或超过全身药物的情况下证明其疗效。尽管具有实用性和持续时间,但是目前使用UVL指导牛皮癣治疗MF / SS患者的做法仍然存在问题,因为与牛皮癣相比,延长生存期和预防疾病进展的目标是CTCL独有的。

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