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首页> 外文期刊>Journal of the International Neuropsychological Society: JINS >Auditory hallucinations and reduced language lateralization in schizophrenia: A meta-analysis of dichotic listening studies
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Auditory hallucinations and reduced language lateralization in schizophrenia: A meta-analysis of dichotic listening studies

机译：精神分裂症的听觉幻觉和减少的语言偏侧化：二项听觉研究的荟萃分析

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Abstract Reduced left-hemispheric language lateralization has been proposed to be a trait marker for schizophrenia, but the empirical evidence is ambiguous. Recent studies suggest that auditory hallucinations are critical for whether a patient shows reduced language lateralization. Therefore, the aim of the study was to statistically integrate studies investigating language lateralization in schizophrenia patients using dichotic listening. To this end, two meta-analyses were conducted, one comparing schizophrenia patients with healthy controls (n = 1407), the other comparing schizophrenia patients experiencing auditory hallucinations with non-hallucinating controls (n = 407). Schizophrenia patients showed weaker language lateralization than healthy controls but the effect size was small (g = -0.26). When patients with auditory hallucinations were compared to non-hallucinating controls, the effect size was substantially larger (g = -0.45). These effect sizes suggest that reduced language lateralization is a weak trait marker for schizophrenia as such and a strong trait marker for the experience of auditory hallucinations within the schizophrenia population. (JINS, 2013, 19, 1-9.)
机译：摘要减少左半球语言偏侧化已被认为是精神分裂症的特征标记，但经验证据尚不明确。最近的研究表明，听觉幻觉对于患者是否表现出减少的语言偏侧性至关重要。因此，该研究的目的是统计性地整合使用二项听觉研究精神分裂症患者语言偏侧化的研究。为此，进行了两次荟萃分析，一个将精神分裂症患者与健康对照（n = 1407）进行比较，另一次将经历幻觉的精神分裂症患者与非卤化性对照（n = 407）进行比较。精神分裂症患者的语言偏侧性弱于健康对照者，但影响大小较小（g = -0.26）。将听觉幻觉患者与非非幻觉对照进行比较时，效果大小明显更大（g = -0.45）。这些效应大小表明，语言偏侧化程度降低是精神分裂症本身的较弱特征标记，也是精神分裂症人群内幻觉经历的强烈特征标记。 （JINS，2013，19，1-9。）

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