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首页> 外文期刊>Journal of the Medical Association of Thailand =: Chotmaihet thangphaet >Effectiveness of conventional phototherapy versus super light-emitting diodes phototherapy in neonatal hyperbilirubinemia
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Effectiveness of conventional phototherapy versus super light-emitting diodes phototherapy in neonatal hyperbilirubinemia

机译：常规光疗与超级发光二极管光疗在新生儿高胆红素血症中的疗效

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Background: Neonatal hyperbilirubinemia is very common. Phototherapy has been used for decades to prevent severe hyperbilirubinemia, which can cause kernicterus. Objective: To compare the effectiveness of two phototherapy devices in reducing plasma bilirubin and duration of phototherapy in non-severe hyperbilirubinemia. Material and Method: This was an open-label randomized controlled trial. Forty healthy infants aged between 1 and 5 days with non-severe hyperbilirubinemia, but to the level requiring phototherapy, were recruited. The phototherapy unit used in the "blue-light" group was the Siriraj Phototherapy Lamp with 6 special blue fl uorescent tubes. The phototherapy unit used in the "light-emitting diodes (LEDs)" group was the Bilitron 3006 with 5 super LEDs. Results: Twenty infants were included in each group. Demographic data and baseline clinical characteristics of infants in both groups were comparable. Median rate (25%, 75%tile) of plasma bilirubin decreasing during phototherapy in the "blue light" was significantly higher than in the "LEDs" group [0.16 (0.09, 0.25) and 0.10 (0.02, 0.17) mg/dL/hour, respectively; p = 0.03]. Duration of phototherapy in "blue light" group was shorter than in "LEDs" group but was not statistically significant. Conclusion: A locally invented phototherapy device with special blue fl uorescent tubes can be more effective than the more expensive commercial super LEDs phototherapy device in decreasing plasma bilirubin.
机译：背景：新生儿高胆红素血症很常见。数十年来，光疗已被用于预防严重的高胆红素血症，后者可导致角膜炎。目的：比较两种光疗设备在非严重高胆红素血症中减少血浆胆红素的有效性和光疗时间。材料和方法：这是一个开放标签的随机对照试验。招募了40例年龄在1至5天之间，患有非严重高胆红素血症但达到需要光疗水平的健康婴儿。 “蓝光”组中使用的光疗设备是Siriraj光疗灯，带有6个特殊的蓝色荧光灯管。 “发光二极管（LED）”组中使用的光疗设备是具有5个超级LED的Bilitron 3006。结果：每组包括20名婴儿。两组婴儿的人口统计学数据和基线临床特征均具有可比性。在“蓝光”中，光疗期间血浆胆红素下降的中位数比率（25％，75％tile）显着高于“ LEDs”组[0.16（0.09，0.25）和0.10（0.02，0.17）mg / dL /小时; p ＝ 0.03]。 “蓝光”组的光疗时间短于“ LEDs”组，但无统计学意义。结论：本地发明的带有特殊蓝色荧光灯管的光疗设备在降低血浆胆红素方面比更昂贵的商用超级LED光疗设备更有效。

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