An efficient synthesis of E-2-amino-4-aryl-8-(arylmethylene)-5,6,7,8-tetrahydrobenzo[d]pyrimidines and their lower analogues

Rammohan Pal; Tapas K. Mandal; Swati Samanta

首页> 外文期刊>Journal of the Indian Chemical Society >An efficient synthesis of E-2-amino-4-aryl-8-(arylmethylene)-5,6,7,8-tetrahydrobenzo[d]pyrimidines and their lower analogues

【24h】

An efficient synthesis of E-2-amino-4-aryl-8-(arylmethylene)-5,6,7,8-tetrahydrobenzo[d]pyrimidines and their lower analogues

机译：E-2-氨基-4-芳基-8-（芳基亚甲基）-5,6,7,8-四氢苯并[d]嘧啶及其低级类似物的有效合成

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Base-catalysed cyclocondensation of α,α'-bis(arylmethylene)cyclohexanones with guanidine hydrochloride has been found to generate E-2-amino-4-aryl-8-(aryimethylene)-5,6,7,8-tetrahydrobenzo[d]pyrimidines in high yield, the structures of which have been established from their analytical and spectral data. The corresponding lower analogues, α,α'-bis(arylmethylene)cyclopentanones also were found to produce similar products viz. E-2-amino-4-aryl-7-(arylmethylene)-cyclopenteno[1,2-d]pyrimidines in comparable yield under the same reaction condition.

机译：已发现碱式催化α，α'-双（芳基亚甲基）环己酮与盐酸胍的环缩合反应可生成E-2-氨基-4-芳基-8-（芳亚甲基）-5,6,7,8-四氢苯并[d]嘧啶类化合物的收率很高，其结构已从其分析和光谱数据确定。还发现相应的低级类似物α，α′-双（芳基亚甲基）环戊酮也可产生类似产物。在相同反应条件下，E-2-氨基-4-芳基-7-（芳基亚甲基）-环戊烯基[1,2-d]嘧啶的收率相当。

著录项

来源
《Journal of the Indian Chemical Society》 |2010年第6期|共5页
作者
Rammohan Pal; Tapas K. Mandal; Swati Samanta;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词
α; α'-Bis(arylmethyiene)cycioa!kanones; guanidine hydrochloride; E-2-amino-4-aryl-8-(arylmethylene)-5; 6; 7; 8-tetrahydrobenzodpyrimidines; E-2-amino-4-aryl-7-(arylmethylene)cyclopenteno1; 2-dpyrimidines;

机译：α;α'-双（芳基亚甲基）环乙酮;盐酸胍;E-2-氨基-4-芳基-8-（芳基亚甲基）-5;6;7;8-四氢苯并[d]嘧啶;E-2-氨基-4-芳基-7-（芳基亚甲基）环戊烯[1;2-d]嘧啶;

相似文献

外文文献
中文文献
专利

1. An efficient synthesis of E-2-amino-4-aryl-8-(arylmethylene)-5,6,7,8-tetrahydrobenzo[d]pyrimidines and their lower analogues [J] . Rammohan Pal, Tapas K. Mandal, Swati Samanta Journal of the Indian Chemical Society . 2010,第6期

机译：E-2-氨基-4-芳基-8-（芳基亚甲基）-5,6,7,8-四氢苯并[d]嘧啶及其低级类似物的有效合成
2. Synthesis of novel bioactive derivatives of 3-(4-chlorophenyl)-2-hydrazino-5,6,7,8-tetrahydrobenzo(b)thieno(2,3-d)pyrimidine- 4(3H)-ones. [J] . Gupta SV, Baheti K, Bora R European Journal of Medicinal Chemistry: Chimie Therapeutique . 2009,第11期

机译：合成3-（4-氯苯基）-2-肼基-5,6,7,8-四氢苯并（b）噻吩并（2,3-d）嘧啶-4（3H）-的新型生物活性衍生物。
3. Derivatives of condensed thieno[2,3-d]-pyrimidines. 20. Synthesis of 2-substituted 5,6-dihydro-8H-pyrano[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-ones and 5,6,7,8-tetrahydrobenzo-[b]thieno[2,3-d]pyrimidin-4-ones [J] . A. P. Mkrtchyan, A. S. Noravyan Chemistry of heterocyclic compounds . 2006,第3期

机译：稠合噻吩并[2,3-d]-嘧啶的衍生物。 20. 2-取代的5,6-二氢-8H-吡喃并[4'，3'：4,5]噻吩并[2,3-d]嘧啶-4（3H）-和5,6,7的合成， 8-四氢苯并[b]噻吩并[2,3-d]嘧啶-4-酮
4. Microwave-Assisted Synthesis of Pyrimidines and 1,2-Dihydro-N-Aryl(Alkyl)-4,6-Dimethyl Pyrimidines [C] . (missing) International symposium on green chemistry in China . 2002

机译：微波辅助合成嘧啶和1,2-二氢 - N-芳基（烷基）-4,6-二甲基嘧啶
5. Targeting pyrimidine synthesis in Plasmodium falciparum with transition state analogues of orotate phosphoribosyltransferase [D] . Zhang, Yong 2011

机译：用乳清酸磷酸核糖基转移酶的过渡态类似物靶向恶性疟原虫中嘧啶的合成
6. Facile Iodine-Catalyzed Michael Addition of Indoles to αα′-Bis(arylmethylene)cyclopentanones: An Efficient Synthesis of E-2-(3-Indolylphenylmethyl)-5-phenylmethylenecyclopentanones [O] . Rammohan Pal, Arpita Das Gupta, Asok K. Mallik 2012

机译：简便的碘催化αα-双（芳基亚甲基）环戊酮的吲哚迈克尔加成反应：E-2-（3-吲哚基苯基甲基）-5-苯基亚甲基环戊酮的高效合成
7. DABCO catalyzed synthesis of new 2-amino-8-arylidene-4-aryl-5,6,7,8-tetrahydrobenzo- 4H-pyran-3-carbonitriles from α,ά-bis(substituted benzylidene)cycloalkanones [O] . Fatemeh Kooti, Mohammad Ali Bigdeli, Gholam Hossein Mahdavinia 2012

机译：DaBCO催化从α，π-双（取代）合成新的2-氨基-8-亚芳基-4-芳基-5,6,7,8-四氢苯并-4-H-吡喃-3-碳腈亚苄基）环烷酮
8. Synthesis of 6-Substituted-2,4-Diamino-5,6,7,8-Tetrahydropyrimido (4-5-d) Pyrimidines. Revised [R] . Delia, T. J., Sami, S. M., Kirt, D. D. 1981

机译：6-取代-2,4-二氨基-5,6,7,8-四氢嘧啶并（4-5-d）嘧啶的合成。修订

An efficient synthesis of E-2-amino-4-aryl-8-(arylmethylene)-5,6,7,8-tetrahydrobenzo[d]pyrimidines and their lower analogues

摘要

著录项

相似文献

相关主题

期刊订阅