• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Veterinary Dentistry >Temporomandibular joint cytokine profiles in the horse
【24h】

Temporomandibular joint cytokine profiles in the horse

机译：马的颞下颌关节细胞因子谱

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

It has been suggested that dental abnormalities lead to temporomandibular joint inflammation and pain that may be mitigated by regular dental care. There is considerable literature on the pathophysiology of equine joint disease including studies on cytokine profiles in diseased appendicular joints. This study examined the effects of age and dental malocclusions summarized as a dental pathology score on equine temporomandibular joint cytokine (IL-1, IL-6, IL-8, TNF alpha and TGF-beta1, -beta2, -beta3) concentrations. TGF-beta3 was not detected in any joint sample. IL-1, IL-6 and TNF alpha were not influenced by age. Foals had significantly lower concentrations of lL-8 and TGF-beta1, and higher levels of TGF-beta2 compared with older horses. Age did not effect cytokine concentration in older horses although there was a trend towards increasing 1L-8 with age. The dental pathology score increased with age in mature horses, however there was no effect of dental pathology score on cytokine concentration. There was no effect of incisor eruption, and presence or number of periodontal lesions on temporomandibular joint cytokine concentration. Our findings indicate that age but not dental pathology affected temporomandibular joint proinflammatory cytokine concentration in this population of horses.
机译：已经提出，牙齿异常导致颞下颌关节发炎和疼痛，可以通过常规的牙齿护理来减轻。有关马关节疾病的病理生理学的文献很多，包括对患病阑尾关节中细胞因子谱的研究。这项研究检查了年龄和牙齿错合的影响，总结为牙齿病理评分对马颞下颌关节细胞因子（IL-1，IL-6，IL-8，TNFα和TGF-beta1，-beta2，-beta3）浓度的影响。在任何关节样本中均未检测到TGF-beta3。 IL-1，IL-6和TNFα不受年龄的影响。与年龄较大的马匹相比，马驹的lL-8和TGF-beta1的浓度明显较低，而TGF-beta2的含量较高。年龄并未影响年老马的细胞因子浓度，尽管有随着年龄增长而增加1L-8的趋势。牙齿病理评分随着年龄的增加而增加，但是牙齿病理评分对细胞因子浓度没有影响。没有门牙喷发，牙周病灶的存在或数量对颞下颌关节细胞因子浓度的影响。我们的研究结果表明年龄，但牙齿病理学未影响该马群中颞下颌关节促炎细胞因子的浓度。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号