Diagnosis and treatment of myelofibrosis: A personal perspective

RashidS.; RadiaD.H.; HarrisonC.N.

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Diagnosis and treatment of myelofibrosis: A personal perspective

机译：骨髓纤维化的诊断和治疗：个人观点

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Myelofibrosis can arise de novo or following one of the other Philadelphia-negative myeloproliferative neoplasms. The differential diagnosis may be challenging and can include other entities which may also express the JAK2 V617F mutation, such as chronic myelomonocytic leukemia and/or refractory anemia with ring sideroblasts. Traditionally a difficult disease to treat with only a small proportion of patients eligible for a curative bone marrow transplant, this field has recently changed radically with the introduction of JAK inihibitors, the first in class being ruxolitinib.

机译：骨髓纤维化可从头发生或继费城阴性的其他骨髓增生性肿瘤之一后出现。鉴别诊断可能具有挑战性，并且可能包括可能也表达JAK2 V617F突变的其他实体，例如慢性粒细胞单核细胞白血病和/或伴有环状成铁细胞的难治性贫血。传统上，这是一种很难治疗的疾病，只有一小部分适合治愈性骨髓移植的患者可以治疗。最近，随着JAK抑制剂的引入，这一领域发生了根本性的改变，其中首例是鲁索替尼。

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《Clinical practice.》 |2013年第4期|共15页
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RashidS.; RadiaD.H.; HarrisonC.N.;
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1. Diagnosis and treatment of myelofibrosis: A personal perspective [J] . RashidS., RadiaD.H., HarrisonC.N. Clinical practice. . 2013,第4期

机译：骨髓纤维化的诊断和治疗：个人观点
2. Differential diagnosis of myelofibrosis based on WHO 2008 criteria: Acute panmyelosis with myelofibrosis, acute megakaryoblastic leukemia with myelofibrosis, primary myelofibrosis and myelodysplastic syndrome with myelofibrosis [J] . BaeE., ParkC.-J., ChoY.-U., International journal of laboratory hematology . 2013,第6期

机译：根据世界卫生组织2008年标准对骨髓纤维化进行鉴别诊断：急性骨髓炎伴骨髓纤维化，急性巨核细胞白血病伴骨髓纤维化，原发性骨髓纤维化和骨髓增生异常综合征伴骨髓纤维化
3. Getting personal on overdiagnosis: O O n defining overdiagnosis from the perspective of the individual person [J] . Hofmann Bj?rn Journal of evaluation in clinical practice . 2018,第5期

机译：从个人人的角度来看个人对过度无限的过度诊断
4. Neurokinin-1 As a Potential Target for the Treatment of Myelofibrosis [C] . P.S. Bandari, H.S. Oh, C. Yook J.A. Potian, European Haematology Association . 2002

机译：Neurokinin-1作为治疗骨髓纤维化的潜在目标
5. Breast cancer at 24: An autoethnography of personal and familial experiences of a breast cancer diagnosis and treatment. [D] . Taylor, Alyssa Page. 2014

机译：24岁的乳腺癌：关于乳腺癌诊断和治疗的个人和家族经历的人种志。
6. JAK Inhibition for the Treatment of Myelofibrosis: Limitations and Future Perspectives [O] . Prithviraj Bose, Srdan Verstovsek 2020

机译：抑制JAK治疗骨髓纤维化的局限性和未来展望
7. Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the international working group for myelofibrosis research and treatment [O] . Barosi G, Mesa RA, Thiele J, 2008

机译：诊断真性红细胞增多症和原发性血小板增多症后骨髓纤维化的建议标准：国际骨髓纤维化研究和治疗工作组的共识声明

Diagnosis and treatment of myelofibrosis: A personal perspective

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