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BDI-modelling of complex intracellular dynamics

机译:复杂细胞内动力学的BDI模拟

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A BDI-based continuous-time modelling approach for intracellular dynamics is presented. It is shown how temporalised BDI-models make it possible to model intracellular biochemical processes as decision processes. By abstracting from some of the details of the biochemical pathways, the model achieves understanding in nearly intuitive terms, without losing veracity: classical intentional state properties such as beliefs, desires and intentions are founded in reality through precise biochemical relations. In an extensive example, the complex regulation of Escherichia coli vis-a-vis lactose, glucose and oxygen is simulated as a discrete-state, continuous-time temporal decision manager. Thus a bridge is introduced between two different scientific areas: the area of BDI-modelling and the area of intracellular dynamics. (c) 2007 Elsevier Ltd. All rights reserved.
机译:提出了一种基于BDI的细胞内动力学连续时间建模方法。它显示了临时的BDI模型如何使将细胞内生化过程建模为决策过程成为可能。通过从生化途径的一些细节中抽象出来,该模型以几乎直觉的方式获得了理解,而又不丧失准确性:通过精确的生化关系在现实中建立了经典的有意状态属性,例如信念,欲望和意图。在一个广泛的例子中,将大肠杆菌相对于乳糖,葡萄糖和氧气的复杂调节模拟为离散状态,连续时间的时间决策管理器。因此,在两个不同的科学领域之间架起了桥梁:BDI建模领域和细胞内动力学领域。 (c)2007 Elsevier Ltd.保留所有权利。

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