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首页> 外文期刊>Journal of Theoretical Biology >A study of entropy/clarity of genetic sequences using metric spaces and fuzzy sets.
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A study of entropy/clarity of genetic sequences using metric spaces and fuzzy sets.

机译:使用度量空间和模糊集研究遗传序列的熵/清晰度。

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摘要

The study of genetic sequences is of great importance in biology and medicine. Sequence analysis and taxonomy are two major fields of application of bioinformatics. In the present paper we extend the notion of entropy and clarity to the use of different metrics and apply them in the case of the Fuzzy Polynuclotide Space (FPS). Applications of these notions on selected polynucleotides and complete genomes both in the I(12xk) space, but also using their representation in FPS are presented. Our results show that the values of fuzzy entropy/clarity are indicative of the degree of complexity necessary for the description of the polynucleotides in the FPS, although in the latter case the interpretation is slightly different than in the case of the I(12xk) hypercube. Fuzzy entropy/clarity along with the use of appropriate metrics can contribute to sequence analysis and taxonomy.
机译:基因序列的研究在生物学和医学上具有重要意义。序列分析和分类学是生物信息学的两个主要应用领域。在本文中,我们将熵和清晰度的概念扩展到使用不同的度量,并将其应用于模糊多核素空间(FPS)的情况。介绍了这些概念在I(12xk)空间中选定的多核苷酸和完整基因组上的应用,以及在FPS中使用它们的表示。我们的结果表明,模糊熵/清晰度的值指示了FPS中多核苷酸描述所必需的复杂程度,尽管在后一种情况下的解释与I(12xk)超立方体的情况略有不同。模糊熵/清晰度以及适当度量的使用可能有助于序列分析和分类。

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