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首页> 外文期刊>Journal of toxicology-Clinical toxicology >Two cases of acute endosulfan toxicity
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Two cases of acute endosulfan toxicity

机译:急性硫丹中毒2例

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摘要

Background. Endosulfan is widely used in insect control and is absorbed by both humans and animals through the intestinal tract, the lungs, and the skin. Organochlorine insecticides are highly toxic compounds that are responsible for a number of severe intoxications worldwide, with several deaths. A 9-year analysis by one of Turkey's poison control centers reported that pesticide intoxications accounted for 8.8% of 25,572 poisoning calls, with 80.3% of them relating to insecticides and 19.7% concerning rodenticides. Case Reports. We present two cases of unintentional exposure to endosulfan, one of which presented with neurological manifestations, liver toxicity, and required mechanical ventilation and emergent hemodialysis; the other had only neurological manifestations and liver toxicity. Conclusion. In cases of endosulfan poisoning, physicians must be aware of neurological manifestations, seizures, and severe metabolic acidosis. If severe metabolic acidosis is present, we suggest that hemodialysis may be an important intervention and should be performed early.
机译:背景。硫丹被广泛用于昆虫控制,被人类和动物通过肠道,肺部和皮肤吸收。有机氯杀虫剂是剧毒化合物,是全球范围内大量严重中毒的原因,有数人死亡。土耳其的一个毒物控制中心之一进行的为期9年的分析报告说,农药中毒占25,572次中毒事件的8.8%,其中80.3%与杀虫剂有关,19.7%与杀鼠剂有关。病例报告。我们介绍了两例意外接触硫丹的情况,其中一例表现为神经系统表现,肝毒性,并需要机械通气和紧急血液透析。另一个仅具有神经系统表现和肝毒性。结论。如果发生硫丹中毒,医生必须注意神经系统表现,癫痫发作和严重的代谢性酸中毒。如果存在严重的代谢性酸中毒,我们建议血液透析可能是重要的干预措施,应尽早进行。

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