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首页> 外文期刊>Journal of toxicology-Clinical toxicology >Pharmacy prescription dispensing errors reported to a regional poison control center.
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Pharmacy prescription dispensing errors reported to a regional poison control center.

机译：药房处方分配错误已报告给区域毒物控制中心。

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OBJECTIVES: To identify the incidence, types, associations, and outcomes of pharmacy prescription dispensing errors reported to a regional poison control center. METHODS: Retrospective chart review over a 35-month period. RESULTS: Of 77,992 drug exposures reported, there were 6450 unintentional therapeutic exposures. Forty were the result of pharmacy prescription dispensing errors. Of these, 20 (50%) were medication substitution errors (wrong drug), 17 (42.5%) were labeling errors (correct drug, wrong formulation or instructions), and 3 (7.5%) were compounding errors (incorrect liquid dilution or capsule preparation). Both compounding and labeling errors were significantly more likely than substitution errors to be order-of-magnitude amounts. Compounding errors were also significantly more likely than labeling errors to be order-of-magnitude amounts. Labeling errors were significantly more likely to be liquids prescribed to children than substitution errors. Compounding errors had significantly more serious outcomes compared with substitution or labeling errors. CONCLUSIONS: Substitution and labeling errors are the most common pharmacy prescription dispensing errors reported to a regional poison control center. Compounding errors have the greatest potential for serious outcomes. Children are particularly at risk because of the increased potential for error in the preparation and use of liquids. Inclusion of scenarios of prescription dispensing errors in the Toxic Exposure Surveillance System database would improve error detection and tracking. Poison control centers may be a source of valuable feedback to physicians and pharmacists.
机译：目的：确定报告给区域毒物控制中心的药房处方分配错误的发生率，类型，关联和结果。方法：回顾性图表审查在35个月内进行。结果：在报告的77,992次药物暴露中，有6450次非故意治疗性暴露。四十是药房处方分配错误的结果。其中，药物替换错误（错误的药物）为20个（50％），标签错误（正确的药物，错误的配方或说明书）为17个（42.5％），复方错误（液体稀释液或胶囊不正确）为3个（7.5％）制备）。与替代错误相比，复合错误和标记错误的可能性要大得多。与标注错误相比，复合错误也更可能是数量级错误。与替换错误相比，标签错误很可能是儿童处方药。与替换或标记错误相比，复合错误的后果要严重得多。结论：替代和标签错误是报告给区域毒物控制中心的最常见的药房处方分配错误。复合错误最有可能带来严重后果。儿童尤其容易受到危险，因为在配制和使用液体时容易出错。在有毒暴露监测系统数据库中包含处方分配错误的场景将改善错误检测和跟踪。毒物控制中心可能是向医生和药剂师提供宝贵反馈的来源。

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