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首页> 外文期刊>Journal of Veterinary Internal Medicine >Infectious agents detected in the feces of diarrheic foals: A retrospective study of 233 cases (2003-2008).
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Infectious agents detected in the feces of diarrheic foals: A retrospective study of 233 cases (2003-2008).

机译:腹泻小马驹粪便中检测到的传染原:233例(2003-2008年)的回顾性研究。

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摘要

BACKGROUND: Diarrhea is common in foals but there are no studies investigating the relative prevalence of common infectious agents in a population of hospitalized diarrheic foals. OBJECTIVES: To determine the frequency of detection of infectious agents in a population of hospitalized foals with diarrhea and to determine if detection of specific pathogens is associated with age, outcome, or clinicopathologic data. ANIMALS: Two hundred and thirty-three foals < or = 10 months of age with diarrhea examined at a referral institution. METHODS: Retrospective case series. Each foal was examined for Salmonella spp., viruses, Clostridium difficile toxins, Clostridium perfringens culture, C. perfringens enterotoxin, Cryptosporidium spp., and metazoan parasites in feces collected at admission or at the onset of diarrhea. RESULTS: At least 1 infectious agent was detected in 122 foals (55%). Rotavirus was most frequently detected (20%) followed by C. perfringens (18%), Salmonella spp. (12%), and C. difficile (5%). Foals < 1 month of age were significantly more likely to be positive for C. perfringens (odds ratio [OR] = 15, 95% confidence interval [CI] = 3.5-66) or to have negative fecal diagnostic results (OR = 3.0, 95% CI = 1.7-5.2) than older foals. Foals > 1 month of age were significantly more likely to have Salmonella spp. (OR = 2.6, 95% CI = 1.2-6.0), rotavirus (OR = 13.3, 95% CI = 5.3-33), and parasites (OR = 23, 95% CI = 3.1-185) detected compared with younger foals. Overall 191 of the 223 foals (87%) survived. The type of infectious agent identified in the feces or bacteremia was not significantly associated with survival. CONCLUSIONS AND CLINICAL IMPORTANCE: In the population studied, foals with diarrhea had a good prognosis regardless of which infectious agent was identified in the feces.
机译:背景:腹泻在小马驹中很常见,但是没有研究调查住院的腹泻小马驹人群中常见传染原的相对患病率。目的:确定腹泻住院小马驹人群中传染病的检测频率,并确定特定病原体的检测是否与年龄,结局或临床病理数据有关。动物:在转诊机构检查的233个驹(小于或等于10个月大,有腹泻)。方法:回顾性病例系列。检查每只驹的沙门氏菌属,病毒,艰难梭菌毒素,产气荚膜梭菌培养物,产气荚膜梭菌肠毒素,隐孢子虫属和在腹泻或发病时收集的后生动物寄生虫。结果:在122只小马驹中至少检测到一种传染原(55%)。轮状病毒的检出率最高(20%),其次是产气荚膜梭菌(18%),沙门氏菌。 (12%)和艰难梭菌(5%)。 1岁以下的驹对产气荚膜梭菌呈阳性的可能性更高(几率[OR] = 15,95%置信区间[CI] = 3.5-66)或粪便诊断结果阴性(OR = 3.0, 95%CI = 1.7-5.2)。大于1个月大的小马患沙门氏菌的可能性更高。与较年轻的小马驹相比,检测到(OR = 2.6,95%CI = 1.2-6.0),轮状病毒(OR = 13.3,95%CI = 5.3-33)和寄生虫(OR = 23,95%CI = 3.1-185)。 223头驹中的191头(87%)存活了下来。粪便或菌血症中鉴定出的传染原类型与存活率无显着相关性。结论和临床意义:在研究人群中,腹泻小马驹的预后良好,而与粪便中确定的是哪种传染源无关。

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