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首页> 外文期刊>Journal of travel medicine. >Imported malaria in children: a comparative study between recent immigrants and immigrant travelers (VFRs).
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Imported malaria in children: a comparative study between recent immigrants and immigrant travelers (VFRs).

机译：儿童输入性疟疾：新移民与新移民之间的比较研究。

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BACKGROUND: In Europe, imported malarial cases occur in returning travelers and immigrants mostly from African countries. There have been an increasing number of cases in the past years in Spain. METHODS: An analysis of all cases of malaria who attended at the Hospital of Mostoles in the Southwest of Madrid from 1995 to 2007 was performed. Clinical, epidemiological, laboratory, and parasitological findings were analyzed and compared between immigrants coming from endemic countries (recent immigrants) and children who traveled to endemic areas to visit friends and relatives (VFRs). RESULTS: Sixty cases of imported malaria were detected. Most of the cases (59 of 60) were acquired in sub-Saharan Africa. The most common species was Plasmodium falciparum (43 of 60). Microscopic examination was positive in 95%, and the polymerase chain reaction (PCR) for Plasmodium achieved additional diagnosis in seven cases. Fourteen cases were VFRs; none of them used appropriate malaria chemoprophylaxis. Fever and thrombocytopenia were significantly more common among VFRs. They also had significantly higher parasite density. Twelve cases were asymptomatic at the time of diagnosis; all of them were recent immigrants. CONCLUSIONS: VFRs account for a significant number of childhood malarial cases. These patients had not taken malaria chemoprophylaxis and malarial cases were more severe. VFR children are a high-risk group, and pretravel advice should underline the risk for malaria. Recent immigrants can be asymptomatic and parasitemias are lower. Therefore, a high index of suspicion is necessary, and PCR for Plasmodium should be performed in case of negative thick smears.
机译：背景：在欧洲，进口的疟疾病例主要来自非洲国家的回返旅行者和移民中。过去几年中，西班牙的案件数量在增加。方法：对1995年至2007年在马德里西南部莫斯托莱斯医院就诊的所有疟疾病例进行了分析。分析，比较了来自流行国家的移民（最近的移民）和前往流行地区探望亲朋好友（VFR）的孩子之间的临床，流行病学，实验室和寄生虫学发现。结果：检出60例输入性疟疾。大多数病例（60个病例中的59个）是在撒哈拉以南非洲获得的。最常见的物种是恶性疟原虫（60种中的43种）。镜检阳性率为95％，疟原虫的聚合酶链反应（PCR）在7例中获得了进一步的诊断。 14例为VFR。他们都没有采取适当的疟疾化学预防措施。发烧和血小板减少症在VFR中更为常见。他们还具有明显更高的寄生虫密度。诊断时无症状12例。他们都是最近的移民。结论：VFR占儿童期疟疾病例的很大一部分。这些患者没有进行疟疾的化学预防，而疟疾病例更为严重。 VFR儿童是高危人群，旅行前建议应强调疟疾风险。最近的移民可能没有症状，寄生虫病率较低。因此，高度怀疑是必要的，如果涂片阴性，则应进行疟原虫PCR。

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