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首页> 外文期刊>Journal of tropical pediatrics. >Food supplementation as an incentive to improve pre-antiretroviral therapy clinic adherence in HIV-positive children-experience from Eastern India
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Food supplementation as an incentive to improve pre-antiretroviral therapy clinic adherence in HIV-positive children-experience from Eastern India

机译：食物补充作为激励措施，以提高印度东部艾滋病毒阳性儿童的抗逆转录病毒治疗前临床依从性

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摘要

Objective: To evaluate the importance of food supplementation as incentive in improving preantiretroviral therapy (pre-ART) adherence, and second its impact on health of HIV-infected children by a clinic-based observational study. Methods: HIV-seropositive children aged between 2 and 12 years were followed-up sequentially for 2 years without and with food supplementation, respectively, with monitoring of disease parameters. The outcome morbidity parameters were compared and correlated. Result: Study showed significant improvement in clinic adherence (r = 0.165, p = 0.027) along with increased mean clinic visit (6.65 ± 1.43 vs. 8.01 ± 1.52, p = 0.000) and mean CD4 count (p = 0.028) with incentive. Provision of incentive correlated well (Pearson's r = 0.345) with number of visits which in turn had strong correlation with weight gain (r = 0.548), episodes of AIDS-defining illnesses (r = -0.412), hospitalization (r = -0.279). Conclusion: Food incentive could enhance pre-ART phase clinic adherence that decreases disease-related morbidities, setting the stage for improved treatment and care of seropositive children in future.
机译：目的：通过一项基于临床的观察性研究，评估补充食品作为改善抗逆转录病毒疗法（pre-ART）依从性的诱因的重要性，以及其次对补充艾滋病毒感染儿童的健康的影响。方法：对年龄在2至12岁之间的HIV血清阳性儿童分别进行随访，随访2年，不添加食物和补充食物，并监测疾病参数。结果发病率参数进行了比较和相关。结果：研究表明，临床依从性显着改善（r = 0.165，p = 0.027），平均门诊次数增加（6.65±1.43 vs. 8.01±1.52，p = 0.000）和平均CD4计数（p = 0.028）。激励的提供与访视次数密切相关（Pearson r = 0.345），而就诊次数与体重增加（r = 0.548），定义艾滋病的疾病（r = -0.412），住院治疗（r = -0.279）密切相关。结论：食物诱因可以增强ART阶段临床前的依从性，从而降低疾病相关的发病率，为将来改善血清反应阳性儿童的治疗和护理奠定基础。

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