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首页> 外文期刊>Journal of voice: official journal of the Voice Foundation >Cricothyroid joint abnormalities in patients with rheumatoid arthritis.
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Cricothyroid joint abnormalities in patients with rheumatoid arthritis.

机译：类风湿关节炎患者的甲状旁腺关节异常。

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The objective of this study was to assess structural and functional abnormalities of the cricothyroid joint (CTJ) in patients with advanced rheumatoid arthritis (RA). A total of 19 subjects--11 patients with advanced RA and eight normal controls--were considered. All subjects underwent laryngeal endoscopy, acoustic analysis, and high-resolution computerized tomography (HRCT). Vocal symptoms, such as hoarseness, loss of range, vocal fatigue, and dyspnea were inquired and acoustic parameters, mainly pitch range, fundamental frequency, habitual pitch, perturbation parameters, and noise-to-harmonic ratio (NHR) and voice turbulence index were measured. Frequencies and means were calculated for categorical and continuous variables. Cases and controls were compared with respect to acoustic analysis, HRCT findings and laryngeal symptoms using nonparametric tests, Mann-Whitney U test for continuous variables and Fishers exact test for categorical variables. Almost half of the patients with RA had loss range and two-thirds had vocal fatigue. Thirty-six percent experienced hoarseness compared with 25% in the control group. 9.1% had decrease in vocal fold mobility and 27% had moderate/severe edema of the vocal folds/arytenoids compared with none in the control group. HRCT showed narrowing in the CTJ in 81.8% and ankylosis in 9.1% compared with none in the control group. 45.5% had an increase in the CTJ density compared with 12.5% in the control group. Acoustic analysis revealed significant decrease in pitch range and maximum phonation time (MPT) and significant increase in perturbation parameters. CTJ is commonly affected in patients with RA. Functional disabilities are crucial especially in professional voice users. Proper awareness is important for early detection and intervention.
机译：这项研究的目的是评估晚期类风湿关节炎（RA）患者的环甲亢关节（CTJ）的结构和功能异常。总共考虑了19名-11岁的晚期RA患者和8名正常对照。所有受试者均接受喉镜检查，声学分析和高分辨率计算机断层扫描（HRCT）。查询声音症状，如声音嘶哑，范围消失，声音疲劳和呼吸困难，并且声学参数主要是音调范围，基频，惯用音调，摄动参数以及噪声与谐波比（NHR）和语音湍流指数测量。计算分类和连续变量的频率和均值。使用非参数检验，连续变量的Mann-Whitney U检验和分类变量的Fishers精确检验，比较了病例和对照的声学分析，HRCT发现和喉部症状。 RA的患者中几乎有一半患有丧失声带，三分之二患有声疲劳。 36％的人感觉嘶哑，而对照组为25％。与对照组相比，9.1％的人的声带活动性下降，27％的人的声带/关节水肿严重。 HRCT显示CTJ变窄为81.8％，强直性病为9.1％，而对照组则没有。与对照组的12.5％相比，CTJ密度增加了45.5％。声学分析显示，音调范围和最大发声时间（MPT）显着减小，摄动参数显着增加。 CTJ通常在RA患者中受到影响。功能障碍至关重要，特别是在专业语音用户中。正确的认识对于及早发现和干预很重要。

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