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首页> 外文期刊>Journal of Veterinary Science >The current epidemiological status of infectious coryza and efficacy of PoulShot Coryza in specific pathogen-free chickens
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The current epidemiological status of infectious coryza and efficacy of PoulShot Coryza in specific pathogen-free chickens

机译：传染性鼻炎的流行病学现状和PoulShot鼻炎在特定无病原体鸡中的功效

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摘要

Infectious coryza (IC) is an infectious disease caused by Avibacterium (Av.) paragallinarum. IC is known to cause economic losses in the poultry industry via decreased egg production in layers. Between 2012 and 2013, Av. paragallinarum was isolated from seven chicken farms by Chungbuk National University. We identified Av. paragallinarum, the causative pathogen of IC by polymerase chain reaction (PCR) and serovar serotype A, by multiplex PCR. Antibiotic sensitivity tests indicated that a few field-isolated strains showed susceptibility to erythromycin, gentamicin, lincomycin, neomycin, oxytetracycline, spectinomycin, and tylosin. A serological survey was conducted to evaluate the number of flocks that were positive for Av. paragallinarum by utilizing a HI test to determine the existence of serovar A. Serological surveys revealed high positivity rates of 86.4% in 2009, 78.9% in 2010, 70.0% in 2011, and 69.6% in 2012. We also challenged specific pathogen-free chickens with isolated domestic strains, ADL121286 and ADL121500, according to the measured efficacy of the commercial IC vaccine, PoulShot Coryza. We confirmed the effectiveness of the vaccine based on relief of clinical signs and a decreased re-isolation rate of ADL121500 strain. Our results indicate IC is currently prevalent in Korea, and that the commercial vaccine is effective at protecting against field strains.
机译：传染性鼻炎（IC）是由副galavilinarum（Av。）引起的传染病。众所周知，集成电路会降低蛋鸡的产蛋量，从而给家禽业造成经济损失。在2012年至2013年之间，平均忠北国立大学从七个养鸡场中分离出了副鞭毛。我们确定了平均多重PCR证实了副鞭毛虫是IC的致病菌，而聚合酶链反应（PCR）和血清型A则是IC的致病菌。抗生素敏感性测试表明，一些现场分离的菌株显示出对红霉素，庆大霉素，林可霉素，新霉素，土霉素，壮观霉素和泰乐菌素的敏感性。进行了血清学调查以评估Av。阳性鸡群的数量。通过HI测试确定血清中存在A血清型。通过血清学调查，阳性率在2009年为86.4％，在2010年为78.9％，在2011年为70.0％，在2012年为69.6％。根据商业IC疫苗PoulShot Coryza的实测功效，使用分离的国内菌株ADL121286和ADL121500。我们通过减轻临床症状和降低ADL121500菌株的再分离率来确认疫苗的有效性。我们的结果表明，IC目前在韩国非常流行，并且该商业疫苗可有效防止田间毒株。

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