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Recombinant chicken infectious coryza vaccine and method for producing the same
Recombinant chicken infectious coryza vaccine and method for producing the same
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机译：重组鸡传染性鼻炎疫苗及其生产方法
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摘要
A recombinant chicken infectious coryza vaccine and a method for producing the same are provided. E. coli that produces a fusion peptide consisting of each peptide derived from the outer membrane protein of Abibacterium paragalinarum A and C as an inclusion body is constructed, and the inclusion body is recovered from the culture in which the E. coli is cultured. A method for producing a recombinant chicken infectious coryza vaccine, comprising a step of purifying and formulating the obtained inclusion body, and a recombinant chicken infectious coryza vaccine containing the fusion peptide as an active ingredient. A linker sequence may be inserted into the binding part of the fusion peptide. As peptides derived from type A and type C bacteria, the amino acid sequence region in or near region 2 that is responsible for the ability to defend against infection is used.
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