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Barriers to Clinical Research Participation Among African Americans

机译:非裔美国人参与临床研究的障碍

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摘要

Clinical research requires representation of racially and ethnically diverse participants to accurately represent the general population. Overall life expectancy of African Americans is shorter than that of the general U.S. population. Compared with the other ethnic groups in the United States, African Americans have higher rates of hypertension, stroke, obesity, and diabetes, and higher rates of mortality related to stroke and cancer. Although many health disparities exist among African Americans, they are well underrepresented in clinical research. This article provides an overview of barriers that may influence participation in clinical research among African Americans. Issues of trust, experimentation, communication, and logistics are the most commonly identified barriers. The barriers and facilitators identified in this review may be useful in the development and implementation of recruitment and research strategies that are culturally sensitive and that may enhance trust and willingness to participate among African Americans.
机译:临床研究要求代表不同种族和种族的参与者,以准确代表一般人群。非裔美国人的总体预期寿命短于美国总人口。与美国其他种族相比,非洲裔美国人的高血压,中风,肥胖和糖尿病发病率更高,与中风和癌症相关的死亡率也更高。尽管非裔美国人之间存在许多健康差异,但在临床研究中它们的代表性仍然很低。本文概述了可能影响非裔美国人参与临床研究的障碍。信任,实验,沟通和后勤问题是最常见的障碍。这次审查中确定的障碍和促进者可能有助于发展和实施具有文化敏感性的招募和研究战略,并可能增强非裔美国人之间的信任和参与的意愿。

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