首页> 外文期刊>Diabetes/metabolism research and reviews >Bone remodelling markers in hypertensive patients with and without diabetes mellitus: link between bone and glucose metabolism.
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Bone remodelling markers in hypertensive patients with and without diabetes mellitus: link between bone and glucose metabolism.

机译:患有或不患有糖尿病的高血压患者的骨重塑标志物:骨与葡萄糖代谢之间的联系。

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摘要

In the present study, bone formation marker, P1NP, was significantly lower in diabetic hypertensive subjects as compared with nondiabetic subjects with and without hypertension. P1NP was inversely associated with parameters of glucose homeostasis such as fasting glucose, HbA1c and positively with homeostasis model assessment-beta cell function. Type 2 DM was associated with an adverse effect on bone formation independently of age, sex and exposure to anti-diabetic drugs.
机译:在本研究中,与没有和没有高血压的非糖尿病受试者相比,糖尿病高血压受试者的骨形成标记物P1NP显着降低。 P1NP与空腹血糖,HbA1c等葡萄糖稳态参数负相关,与稳态模型评估β细胞功能正相关。 2型DM与年龄,性别和服用抗糖尿病药物无关,对骨骼形成有不利影响。

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