Vildagliptin add-on to metformin versus metformin uptitration in Chinese patients with type 2 diabetes: A sub-group analysis of the VISION study

LINONG JI

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Vildagliptin add-on to metformin versus metformin uptitration in Chinese patients with type 2 diabetes: A sub-group analysis of the VISION study

机译：中国2型糖尿病患者使用二甲双胍加维达列汀与二甲双胍增高的比较：VISION研究的亚组分析

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Aims:?Obesity and age are two independent risk factors for type 2 diabetes mellitus (T2DM), and they affect disease progression and treatment options. In the VISION study (VIdagliptin 50 mg bid as an add-on to metformin 500 mg bid compared with metformin up to 1000 mg bid in Chinese patients with type 2 diabeteS Inadequately controlled on metformin 500 mg bid mONotherapy), vildagliptin plus low-dose metformin demonstrated non-inferior and even superior HbA1c reduction versus metformin uptitration monotherapy (?0.54% versus ?0.40%, p?

机译：目的：肥胖和年龄是2型糖尿病（T2DM）的两个独立的危险因素，它们影响疾病的进展和治疗选择。在VISION研究中（中国2型糖尿病患者二甲双胍500毫克比格列汀50毫克比二甲双胍最多增加1000毫克，二甲双胍对500毫克二甲双胍的控制不充分），维达列汀加小剂量二甲双胍与二甲双胍单药治疗相比，HbA1c的降低效果不亚于甚至更好（？0.54％vs？0.40％，p？<？0.0001）。在这里，我们介绍了这项研究的亚组分析结果。

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《Diabetes/metabolism research and reviews》 |2015年第1期|共14页
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LINONG JI;
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中图分类内分泌腺疾病及代谢病;
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1. Vildagliptin add-on to metformin versus metformin uptitration in Chinese patients with type 2 diabetes: A sub-group analysis of the VISION study [J] . LINONG JI Diabetes/metabolism research and reviews . 2015,第Suppla1期

机译：中国2型糖尿病患者使用二甲双胍加维达列汀与二甲双胍增高的比较：VISION研究的亚组分析
2. “A Comparative Study to Evaluate the Efficacy and Safety of Vildagliptin as an Add-on Therapy to a Low-Dose Metformin vs an Uptitration of Metformin in Type 2 DM Patients [J] . Nancy Thomas, Subin Mary Zachariah, India. International Journal of Pharmaceutical Sciences Review and Research . 2013,第2期

机译：“一项比较研究，评估在2型DM患者中，维格列汀作为小剂量二甲双胍与二甲双胍增高的附加疗法的疗效和安全性
3. A Comparative Study to Evaluate the Efficacy and Safety of Vildagliptin as an Add-on Therapy to a Low-Dose Metformin vs an Uptitration of Metformin in Type 2 DM Patients” [J] . Basavaraj Bhandare, Satyanarayana. V, Jyotirmoy Adhikary. International Journal of Pharmaceutical Sciences Review and Research . 2013,第2期

机译：评价维拉格列汀作为小剂量二甲双胍与二甲双胍增高的联合疗法的疗效和安全性的比较研究”
4. Controlled Release of Metformin Loaded Polyvinyl Alcohol (PVA) Microbubble/Nanoparticles Using Microfluidic Device for the Treatment of Type 2 Diabetes Mellitus [C] . Sumeyye Cesur, Muhammet Emin Cam, Fatih Serdar Sayin, International work-conference on bioinformatics and biomedical engineering . 2020

机译：使用微流体装置控制二甲双胍负载的聚乙烯醇（PVA）微泡/纳米颗粒的控释，用于治疗2型糖尿病
5. Metformin use and the incidence of colorectal and lung cancer in patients with type 2 diabetes mellitus [D] . Smiechowski, Brielan. 2012

机译：二甲双胍的使用与2型糖尿病患者大肠癌和肺癌的发生率
6. Efficacy and safety of combination therapy with vildagliptin and metformin versus metformin up-titration in Chinese patients with type 2 diabetes mellitus: study design and rationale of the vision study [O] . Li-Nong Ji, Chang-Yu Pan, Ju-Ming Lu, 2013

机译：维达列汀与二甲双胍联合治疗与二甲双胍调高联合治疗在中国2型糖尿病患者中的疗效和安全性：研究设计和视觉研究的原理
7. Comparison of the Effectiveness and Safety of Vildagliptin Add-On to Metformin Versus Other Oral Dual Antidiabetes Agents in Patients with Type 2 Diabetes: The China Prospective Diabetes Study [O] . Li Zang, Yin Han, Lixian Chen, 2019

机译：vilyagliptin加载作用于2型糖尿病患者与其他口服双抗体剂的效果和安全性比较：中国前瞻性糖尿病研究

Vildagliptin add-on to metformin versus metformin uptitration in Chinese patients with type 2 diabetes: A sub-group analysis of the VISION study

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