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首页> 外文期刊>Journal of Surgical Oncology >Clinicopathological characteristics of intrahepatic cholangiocellular carcinoma presenting intrahepatic bile duct growth.
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Clinicopathological characteristics of intrahepatic cholangiocellular carcinoma presenting intrahepatic bile duct growth.

机译：表现为肝内胆管生长的肝内胆管细胞癌的临床病理特征。

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BACKGROUND: Intrahepatic cholangiocellular carcinoma (ICC) presenting intraductal growth (IG) has distinct clinicopathological features with a favorable prognosis. The mass-forming (MF) plus IG type of ICC has not been previously investigated. METHODS: One hundred forty-four patients with ICC underwent surgical resections and were classified according to the macroscopic type. The clinicopathological features of the IG type (n = 7) and MF plus IG type (n = 14) were retrospectively analyzed. The clinicopathological differences between the MF plus IG type and MF plus periductal infiltrating (PI) type (n = 37) were compared. RESULTS: All of the patients with the IG type had no sign of recurrence and survived. The 5-year overall survival rates was significantly better in the MF plus IG type than in the MF plus PI type (41.3% vs. 13.3%, P = 0.034). Significant differences were recognized between the MF plus IG type and MF plus PI type, in terms of vascular resection (P = 0.030), mucosal extension (P = 0.006), and postoperative recurrence (P = 0.004). CONCLUSIONS: The MF plus IG type had significantly better prognosis than the MF plus PI type. The IG type and MF plus IG type should be distinguished from other types even if hepatic hilar confluence is involved, because of the favorable outcome after surgery.
机译：背景：表现为导管内生长（IG）的肝内胆管细胞癌（ICC）具有独特的临床病理特征，预后良好。 ICC的质量形成（MF）加IG类型尚未进行过研究。方法：对144例ICC患者进行了手术切除，并根据宏观类型进行了分类。回顾性分析IG型（n = 7）和MF加IG型（n = 14）的临床病理特征。比较了MF加IG型和MF加导管周围浸润（PI）型的临床病理差异（n = 37）。结果：所有IG型患者均未见复发迹象，并存活。 MF加IG型患者的5年总生存率明显高于MF加PI型患者（41.3％vs. 13.3％，P = 0.034）。 MF加IG型和MF加PI型之间在血管切除（P = 0.030），粘膜扩张（P = 0.006）和术后复发（P = 0.004）方面存在显着差异。结论：MF加IG型的预后明显优于MF加PI型。即使涉及肝门融合，也应将IG型和MF加IG型与其他类型区分开，因为术后效果良好。

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