A Case of Metastatic Pancreatic Adenocarcinoma With Prolonged Survival After Combination of Neoadjuvant FOLFIRINOX Therapy and Synchronous Distal Pancreatectomy and Hepatectomy

Neofytou Kyriakos; Giakoustidis Alexandros; Smyth Elizabeth C.; Cunningham David; Mudan Satvinder

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A Case of Metastatic Pancreatic Adenocarcinoma With Prolonged Survival After Combination of Neoadjuvant FOLFIRINOX Therapy and Synchronous Distal Pancreatectomy and Hepatectomy

机译：新辅助FOLFIRINOX联合同步异位胰腺切除和肝切除术后转移性胰腺癌生存期延长的病例

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In this case report we detail the treatment of a patient with pancreatic ductal adenocarcinoma and a solitary liver metastasis who received nine cycles of FOLFIRINOX therapy with favourable response. The patient subsequently underwent synchronous distal pancreatectomy and hepatectomy with an R0 resection followed by three further cycles of FOLFIRINOX. At the last follow-up, 2 years from operation and 28 months from the diagnosis of metastatic pancreatic adenocarcinoma the patient remains disease free. J. Surg. Oncol. 2015 111:768-770. (c) 2014 Wiley Periodicals, Inc.

机译：在本病例报告中，我们详细介绍了接受9个周期的FOLFIRINOX治疗并产生良好反应的胰腺导管腺癌和孤立性肝转移患者的治疗方法。患者随后接受同步远端胰切除术和肝切除术，并进行R0切除，之后再进行三个FOLFIRINOX周期。在最后一次随访中，手术后2年和诊断为转移性胰腺腺癌后28个月，患者仍然没有疾病。 J. Surg。 Oncol。 2015 111：768-770。（c）2014年威利期刊有限公司

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《Journal of Surgical Oncology》 |2015年第6期|共3页
作者
Neofytou Kyriakos; Giakoustidis Alexandros; Smyth Elizabeth C.; Cunningham David; Mudan Satvinder;
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正文语种 eng
中图分类肿瘤学;
关键词
metastatic pancreatic adenocarcinoma; neoadjuvant; FOLFIRINOX; surgery; resection;

机译：转移性胰腺腺癌;新辅助;FOLFIRINOX;手术;切除;

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1. A Case of Metastatic Pancreatic Adenocarcinoma With Prolonged Survival After Combination of Neoadjuvant FOLFIRINOX Therapy and Synchronous Distal Pancreatectomy and Hepatectomy [J] . Neofytou Kyriakos, Giakoustidis Alexandros, Smyth Elizabeth C., Journal of Surgical Oncology . 2015,第6期

机译：新辅助FOLFIRINOX联合同步异位胰腺切除和肝切除术后转移性胰腺癌生存期延长的病例
2. Full dose neoadjuvant FOLFIRINOX is associated with prolonged survival in patients with locally advanced pancreatic adenocarcinoma [J] . Khushman Mohd, Dempsey Naomi, Maldonado Jennifer Cudris, Pancreatology: official journal of the International Association of Pancreatology (IAP) ... [et al.] . 2015,第6期

机译：全剂量新辅助FOLFIRINOX与局部晚期胰腺癌患者的生存期延长有关
3. Prolonged Complete Response in a Patient with Metastatic Pancreatic Adenocarcinoma after FOLFIRINOX Chemotherapy and Maintenance with FOLFIRI [J] . ChristosNikolaou, AlexiosMatikas, MariaPapavasilopoulou, Case Reports in Oncological Medicine . 2015,第3期

机译：延长胰腺腺癌后的患者的延长完全反应，然后用folfiri维持和维修
4. Texture Analysis For Survival Prediction of Pancreatic Ductal Adenocarcinoma Patients with Neoadjuvant Chemotherapy [C] . Jayasree Chakraborty, Liana Langdon-Embry, Joanna G. Escalon, Conference on imaging processing . 2016

机译：纹理分析对胰腺癌新辅助化疗患者生存率的预测
5. Mechanism of action of, and combination chemotherapy with isoprenoids perillyl alcohol, farnesol, and geraniol in in vitro and in vivo models of human pancreatic adenocarcinoma. [D] . Wiseman, Dean Allen. 2004

机译：异戊二烯类紫苏醇，法尼醇和香叶醇在人胰腺癌的体内和体外模型中的作用机理以及联合化疗的作用。
6. Long-term Disease-free Survival Following Combination Multi-visceral and Metastatic Resection with Neoadjuvant FOLFIRINOX for Pancreatic Adenocarcinoma: A Case Report [O] . Mikael Sodergren, Kirsty Brammer, David Cunningham, -1

机译：多脏器和转移性切除联合新辅助FOLFIRINOX治疗胰腺腺癌后的长期无病生存：一例报告
7. Long-term Disease-free Survival Following Combination Multi-visceral and Metastatic Resection with Neoadjuvant FOLFIRINOX for Pancreatic Adenocarcinoma: A Case Report. [O] . Sodergren M, Brammer K, Cunningham D, 2015

机译：新辅助FOLFIRINOX联合多脏器联合转移治疗胰腺癌的长期无病生存率1例。

A Case of Metastatic Pancreatic Adenocarcinoma With Prolonged Survival After Combination of Neoadjuvant FOLFIRINOX Therapy and Synchronous Distal Pancreatectomy and Hepatectomy

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