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TEMBLOR - Perspectives of EBI database services

机译:TEMBLOR-EBI数据库服务的观点

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Rapid progress in sequencing during the last few years has led to the publication of the sequences of around 70 complete genomes. At least twice that number is expected to be completed by the end of 2002. The availability of complete genomic data allows a whole range of new large-scale experiments such as the generation of whole-genome gene expression data, high-throughput protein identification by mass spectrometry, analysis of protein-protein interactions by two-hybrid-systems, phage-display, tandem-affinity-purification or other methods. These and other types of high-throughput experiments all produce large quantities of data, which must be stored in robust databases to enable their analysis and exploitation. Much of this data is currently spread over many databases with differing structures and locations making it difficult for users to have an integrated view of the information. To cope with data of such magnitude and complexity, higher interoperability of databases is essential.
机译:在过去的几年中,测序技术的快速发展已导致大约70个完整基因组序列的发布。预计到2002年底将完成该数目的至少两倍。完整的基因组数据的可用性允许进行一系列新的大规模实验,例如生成全基因组基因表达数据,通过质谱,通过双杂交系统分析蛋白质-蛋白质相互作用,噬菌体展示,串联亲和纯化或其他方法。这些以及其他类型的高通量实验都会产生大量数据,必须将这些数据存储在强大的数据库中才能进行分析和利用。当前,许多数据分布在具有不同结构和位置的许多数据库中,从而使用户难以获得信息的完整视图。为了处理如此庞大和复杂的数据,更高的数据库互操作性至关重要。

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