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Clinical studies of sixteen cases with pulmonary cryptococcosis mainly with respect to serum level of cryptococcal antigen

机译:主要针对血清隐球菌抗原水平的16例肺隐球菌病的临床研究

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Clinical studies of sixteen cases with pulmonary cryptococcosis, during the past six years between 1998 and 2004, were peformed mainly with respect to serum cryptococcal antigen titer. Serum cryptococcal antigen was positive in twelve of 16 cases, the other three cases were diagnosed by VATS, the other one by positive culture of cryptococcus in BALF. In these twelve cases, the serum cryptococcal antigen titer was continuously tested after treatment. The serum cryptococcal antigen titer decreased from half to 6 months after treatment. And the cryptococcal Ag changed to negative in six of the 12 cases by antifungal agents from 5 to 19 months. But four cases whose pneumonia was severe tended to have a high titer level of cryptococcal antigen and were positive for a long period. In the Chest CT of four pulmonary cryptococcosis case with negative cryptococcal antigen, all of the maximum nodule size was less than or equal to 15mm in diameter.
机译:在1998年至2004年的过去6年中,对16例肺隐球菌病的临床研究主要针对血清隐球菌抗原滴度进行。血清隐球菌抗原在16例中的12例中为阳性,其他3例通过VATS诊断,另一例通过BALF中隐球菌的阳性培养。在这十二种情况下,治疗后连续测试血清隐球菌抗原滴度。治疗后血清隐球菌抗原滴度从半个月降低到6个月。在5到19个月的抗真菌药治疗的12例病例中,有6例的隐球菌Ag变为阴性。但是,四例严重的肺炎患者往往具有较高的隐球菌抗原滴度水平,并且长期呈阳性。在四个隐球菌抗原阴性的肺隐球菌病病例的胸部CT中,所有最大结节直径均小于或等于15mm。

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