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首页> 外文期刊>感染症学雑誌 >Usefulness of urinary antigen and sputum Gram stain for rapid diagnosis of pneumococcal respiratory infections
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Usefulness of urinary antigen and sputum Gram stain for rapid diagnosis of pneumococcal respiratory infections

机译：尿抗原和痰革兰氏染色对快速诊断肺炎球菌呼吸道感染的有用性

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摘要

We evaluated the usefulness of a rapid urinary antigen detection kit (Binax NOW) to detect Streptococcus pneumoniae in the early diagnosis of pneumococcal respiratory tract infections in 313 patients with presumptive respiratory tract infections. We compared results of this test with those of sputum Gram staining. Urinary antigen and sputum Gram staining were respectively positive in 37 and 36 of 57 patients with pneumococcal respiratory infections. The urinary antigen showed moderate positive rate of 64.9% and low false positive rate of 2.3%. The sputum Gram staining also showed moderate positive rate of 64.3% and low false positive rate of 3.5%. Pneumococcal antigen was more frequently detected in patients with severe pneumococcal infections (6/6) than those with mild (5/10) and moderate (26/41) infections. Of the 9 patients who had received antibiotics before testing, antigen was detected in 8 but positive results of sputum Gram stain were in 4. In conclusion, urinary antigen test is a useful test for early diagnosis of pneumococcal respiratory infections especially in adult patients with moderate or severe infections for whom demonstrative results of a sputum Gram stain is unavailable, even after commencement of antibiotic treatment.
机译：我们评估了快速尿液抗原检测试剂盒（Binax NOW）在313例推定性呼吸道感染患者的肺炎球菌呼吸道感染的早期诊断中检测肺炎链球菌的有效性。我们将该测试结果与痰革兰氏染色结果进行了比较。 57例肺炎球菌呼吸道感染患者中的37例和36例尿液抗原和痰革兰氏染色阳性。尿抗原的中度阳性率为64.9％，假阳性率较低为2.3％。痰革兰氏染色还显示中度阳性率为64.3％，假阳性率较低为3.5％。严重肺炎球菌感染（6/6）患者比轻度（5/10）和中度（26/41）感染患者更经常检测到肺炎球菌抗原。在检测前接受抗生素治疗的9例患者中，有8例检出了抗原，而痰革兰氏染色阳性的结果为4例。总之，尿液抗原检测是一种早期诊断肺炎球菌呼吸道感染的有用方法，特别是对于中度成年患者或严重的感染，即使开始抗生素治疗后，也无法获得痰革兰氏染色的示范性结果。

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