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Clinical and bacterial analysis of pediatric urinary tract infection

机译：小儿尿路感染的临床和细菌学分析

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We analyzed the clinical and bacterial backgrounds of 120 patients with pediatric urinary tract infection (UTI). Escherichia coli was the main pathogen recovered from 98 patients (81.7%). All causative agents isolated from 50 uncomplicated UTI cases were E. coli. Of 98 cases of E. coli UTI, 71 were treated with second-generation cephems, whose therapeutic effect was equal to that of third and fourth-generation cephems. MIC50 and MIC90 (microg/mL) for E. coli were as follows: cefazolin :2, 4; cefmetazole: < or = 0.5, 2; and ceftazidime: < or = 0.25, < or = 0.25. Yearly decline in susceptibility was not observed, but MIC elevation for third generation cephems (< or = 2 microg/mL) including ceftazidime was seen in six isolates. Careful monitoring of susceptibility trends is therefore necessary for appropriate antimicrobial therapy.
机译：我们分析了120例小儿尿路感染（UTI）的临床和细菌背景。大肠杆菌是从98例患者中回收的主要病原菌（81.7％）。从50例单纯性UTI病例中分离出的所有病原体均为大肠杆菌。在98例UTI大肠杆菌中，有71例使用第二代头孢治疗，其治疗效果与第三代和第四代头孢相同。大肠杆菌的MIC50和MIC90（微克/毫升）如下：头孢唑林：2，4;头孢美唑：<或= 0.5，2;和头孢他啶：<或= 0.25，<或= 0.25。没有观察到每年的药敏性下降，但是在六个分离物中发现包括头孢他啶的第三代头孢（<或= 2 microg / mL）的MIC升高。因此，对于适当的抗微生物治疗，必须仔细监测药敏趋势。

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