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Two cases of HIV-1 acute infection with antibody negative by immunochromatography method

机译:免疫层析法检测2例HIV-1抗体阴性的急性感染

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摘要

We found two cases of HIV-1 acute infection, confirmed by nucleic amplification test (NAT) and/or RT-PCR, with HIV-1 antibody negative by immunochromatography (IC) method but weakly positive by particle agglutination (PA) test. These cases suggested that IC method was less sensitive than PA test in the detection of acute infections. It is necessary to execute the post counseling that considers the possibility of the acute infection in public health centers and testing places where IC method is used for the screening test. It is also important to recommend taking the following re-examination after a certain period to a person who seems to have had a chance of infection in a short time before testing.
机译:我们发现了2例HIV-1急性感染,通过核酸扩增试验(NAT)和/或RT-PCR证实,HIV-1抗体通过免疫色谱(IC)方法阴性,但通过颗粒凝集(PA)试验弱阳性。这些案例表明,IC方法在检测急性感染方面不如PA检测灵敏。有必要进行咨询后,考虑在使用IC方法进行筛查测试的公共卫生中心和测试场所中可能发生急性感染的可能性。同样重要的是,建议在一段时间后,对似乎在测试前不久有感染机会的人进行以下再次检查。

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