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Drug susceptibility of Trichosporon beigelii isolated from urine and clinical features of their hosts

机译:从尿液中分离出米色毛癣菌的药物敏感性及其宿主的临床特征

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摘要

We investigated of Trichosporon beigelii by a surveillance study for two years in the Tokyo Metropolitan Police Hospital. T. beigelii was frequently found in the urine in aged patients with indwelled urethral catheter and in serious stage patients associated with malignancy. T. beigelii was in all cases isolated from the samples of patients in a hospital stay over 5 days. Minimum inhibitory concentrations (MICs) of anti-fungal agents against T. beigelii were determined by agar-dilution method. Fluconazole resistant strains of T. beigelii were found by this method. Microscopic examination revealed phagocyted T. beigelii in multinucleated neutrophils in some cases. In conclusion, T. beigelii might be suggested a causative organism of opportunistic infection in urinary diseases.
机译:我们在东京都警察医院进行了为期两年的监视研究,调查了米氏毛癣菌。在患有留置导尿管的老年患者和严重恶性肿瘤患者的尿液中经常发现米色丁香。在所有情况下,均从医院住院5天以上的患者样本中分离出米色T.通过琼脂稀释法确定抗真菌剂对米色锥虫的最小抑制浓度(MIC)。通过这种方法发现了耐氟康唑的米色锥虫菌株。显微镜检查发现在某些情况下多核中性粒细胞中吞噬了米色锥虫。总之,可能提示米色锥虫是泌尿系统疾病机会性感染的病原体。

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