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Human herpes virus and malignancies

机译:人疱疹病毒和恶性肿瘤

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摘要

Two type of human herpes viruses, type 4(Epstein Barr virus, EBV) and type 8(HHV8) are known to cause malignancies. Among those, EBV is the very most popular human oncovirus. It can cause malignant lymphomas of various subtypes including Burkitt's lymphoma, opportunistic lymphomas, pyothorax-associated lymphoma, nasal T/NK cell lymphoma, Hodgkin's disease and a part of diffuse large cell lymphomas. HHV8 is a new member of human oncovirus associating with primary effusion lymphoma, a part of solid lymphoma taking diffuse large or anaplastic large cell morphology, and the Castleman's tumor. Introduction of histopathologic methodologies makes the correct diagnosis of those herpes virus-associated tumors an easy routine test.
机译:已知两种类型的人类疱疹病毒会引起恶性肿瘤,即4型(Epstein Barr病毒,EBV)和8型(HHV8)。其中,EBV是最流行的人类肿瘤病毒。它可引起各种亚型的恶性淋巴瘤,包括伯基特淋巴瘤,机会性淋巴瘤,脓胸相关淋巴瘤,鼻T / NK细胞淋巴瘤,霍奇金病和部分弥漫性大细胞淋巴瘤。 HHV8是人类肿瘤病毒的新成员,与原发性渗出性淋巴瘤,散发性大或间变性大细胞形态的实体淋巴瘤以及Castleman肿瘤相关。引入组织病理学方法使对那些与疱疹病毒有关的肿瘤的正确诊断成为一项简单的常规检查。

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