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Past trends in hepatitis C virus infection and route of transmission in Japan

机译:日本丙型肝炎病毒感染和传播途径的过去趋势

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摘要

In Japan, it is known that the prevalence of hepatitis C virus(HCV) is high among the older people over 60 years of age in sharp contrast to the low prevalence among those under 30. The annual incidence rate of HCV carriers in general population remains quite low to be 1.8-3.4 per 100,000 person-year. On the other hand, HCV prevalence among intravenous drug users(IVDU) is still greater than 60%. Taking into account this epidemiological pattern together with the historical fact that Japan experienced an explosion of drug abuse among young generation of 15 to 25 years old in the period of post World War II turmoil together with the poor sanitary and medical conditions, it is suggested that a great wave of HCV spread in Japan occurred most likely in 1960's to 1970's. The spread then may have gradually fallen to the range today.
机译:在日本,众所周知,丙型肝炎病毒(HCV)的患病率在60岁以上的老年人中较高,而30岁以下的人群中的患病率较低。普通人群中HCV携带者的年发病率仍然保持相当低,为每100,000人年1.8-3.4。另一方面,静脉吸毒者(IVDU)的HCV患病率仍高于60%。考虑到这种流行病学模式以及历史事实,即在第二次世界大战后的动荡时期,日本在15至25岁的年轻一代中滥用毒品的人数激增,加上恶劣的卫生和医疗条件,建议HCV在日本的广泛传播极有可能在1960年代至1970年代发生。当时的价差可能已逐渐下降到今天的范围。

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