• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Comparative Medicine >Three-Dimensional Time-of-Flight Magnetic Resonance Angiography of Intracranial Vessels in a Canine Model of Ischemic Stroke with Permanent Occlusion of the Middle Cerebral Artery.
【24h】

Three-Dimensional Time-of-Flight Magnetic Resonance Angiography of Intracranial Vessels in a Canine Model of Ischemic Stroke with Permanent Occlusion of the Middle Cerebral Artery.

机译：缺血性卒中伴永久性大脑中动脉闭塞的犬模型中颅内血管的三维飞行时间磁共振血管造影。

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The purpose of this study was to evaluate the potential efficacy of 3-dimensional time-of-flight magnetic resonance angiography (TOF-MRA) to validate a canine ischemic stroke model. Ischemic stroke was induced through permanent middle cerebral artery occlusion (MCAO) in 5 healthy Beagle dogs. T2-turbo spin echo images and TOF-MRA were obtained with a 1.5-T magnetic resonance system before and 3 and 10 d after MCAO. In 3 dogs, angiograms of the brain obtained at 3 d after MCAO showed complete occlusion of the MCA; in addition, T2 hyperintensities were present unilaterally in the striatocapsular and cerebral cortex lesions. Partial occlusion of the proximal part of the MCA was identified in the 2 remaining dogs, with T2 hyperintensities present only in the striatocapsular lesions. The occluded sites were confirmed at necropsy. The results of this study demonstrate the potential of TOF-MRA to provide a detailed description of intracranial arteries and aid in the evaluation of flow impairment in a canine MCAO model.
机译：这项研究的目的是评估三维飞行时间磁共振血管造影（TOF-MRA）验证犬缺血性中风模型的潜在功效。通过永久性大脑中动脉阻塞（MCAO）在5只健康的Beagle犬中诱发缺血性中风。在MCAO之前，MCAO之后3和10 d用1.5-T磁共振系统获得了T2-turbo自旋回波图像和TOF-MRA。在3只狗中，MCAO后3 d获得的脑血管造影显示MCA完全闭塞。此外，纹状体囊和大脑皮层病变中单方面存在T2高信号。在剩下的2只狗中发现了MCA近端的部分闭塞，其中T2高信号仅存在于纹状体囊状病变中。尸检时确认咬合部位。这项研究的结果证明了TOF-MRA可能提供颅内动脉的详细描述，并有助于评估犬MCAO模型中的血流障碍。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号