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首页> 外文期刊>Comparative Medicine >High Incidence of Scrotal Hernias in a Closed Colony of FVB Mice
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High Incidence of Scrotal Hernias in a Closed Colony of FVB Mice

机译：FVB小鼠封闭菌落阴囊疝的高发病率

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摘要

Although inguinal hernias are rarely reported to occur in mice, a high incidence of scrotal hernias was observed in a closed breeding colony of FVB/N mice. Unilateral or bilateral hernias occurred in more than 20% of the male mice in the colony that were available for necropsy over 3 inbred and 1 outcross generations; no female mice were affected. Organs commonly present within the hernial sac included the cecum and seminal vesicles. Hernias did not adversely affect the fertility or lifespan of the affected male mice. Although the condition was heritable, no clear pattern of transmission was evident.
机译：尽管很少报道腹股沟疝在小鼠中发生，但在FVB / N小鼠的封闭繁殖群中发现阴囊疝的发生率很高。单侧或双侧疝发生在该群体中超过20％的雄性小鼠中，可在3个近交世代和1个异交世代中进行尸检。没有雌性小鼠受到影响。疝囊中普遍存在的器官包括盲肠和精囊。疝气不会对受影响的雄性小鼠的生育力或寿命产生不利影响。尽管情况是可遗传的，但没有明显的传播方式。

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