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首页> 外文期刊>Comparative Medicine >Natural Infection of Burkholderia pseudomallei in an Imported Pigtail Macaque (Macaca netnestrina) and Management of the Exposed Colony
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Natural Infection of Burkholderia pseudomallei in an Imported Pigtail Macaque (Macaca netnestrina) and Management of the Exposed Colony

机译：进口猪尾猕猴（Macaca netnestrina）的Burkholderia pseudomallei的自然感染和暴露菌落的管理

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摘要

Identification of the select agent Burkholderia pseudomallei in macaques imported into the United States is rare. A purpose-bred, 4.5-y-old pigtail macaque (Macaca nemestrina) imported from Southeast Asia was received from a commercial vendor at our facility in March 2012. After the initial acclimation period of 5 to 7 d, physical examination of the macaque revealed a subcutaneous abscess that surrounded the right stifle joint. The wound was treated and resolved over 3 mo. In August 2012, 2 mo afterthe stifle joint wound resolved, the macaque exhibited neurologic clinical signs. Postmortem microbiologic analysis revealed that the macaque was infected with B. pseudomallei. This case report describes the clinical evaluation of a B. pseudomallei-iniected macaque, management and care of the potentially exposed colony of animals, and protocols established for the animal care staff that worked with the infected macaque and potentially exposed colony. This article also provides relevant information on addressing matters related to regulatory issues and risk management of potentially exposed animals and animal care staff.
机译：在进口到美国的猕猴中，很少能找到选择剂Burkholderia pseudomallei。 2012年3月，从我们的工厂从一家商业供应商处收到了从东南亚进口的专用的4.5岁猪尾猕猴（Macaca nemestrina）。经过5到7 d的初始适应期后，对猕猴进行了身体检查皮下脓肿围绕着右脚踝关节。治疗伤口并在3个月内解决。 2012年8月，在窒息关节伤口愈合2个月后，猕猴表现出神经系统的临床症状。验尸后的微生物学分析表明，猕猴感染了假苹果芽孢杆菌。该病例报告描述了假双歧杆菌感染的猕猴的临床评估，可能暴露的动物菌落的管理和护理，以及为与感染的猕猴和可能暴露的菌落一起工作的动物护理人员建立的协议。本文还提供了有关解决与可能暴露的动物和动物护理人员的监管问题和风险管理有关的问题的相关信息。

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